A79922
9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate
≥99%
동의어(들):
THA hydrochloride hydrate, Tacrine hydrochloride, Tetrahydroaminacrine hydrochloride hydrate
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C13H14N2 · HCl · xH2O
CAS 번호:
Molecular Weight:
234.72 (anhydrous basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥99%
Form:
solid
assay
≥99%
form
solid
mp
284-286 °C (lit.)
SMILES string
O.Cl.Nc1c2CCCCc2nc3ccccc13
InChI
1S/C13H14N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H;1H2
InChI key
PXGRMZYJAOQPNZ-UHFFFAOYSA-N
Application
9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate is a well-known cholinesterase inhibitor commonly used in pharmacological studies.
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
New Tacrines as Anti-Alzheimer's Disease Agents. The (Benzo) Chromeno-PyranoTacrines.
Oset-Gasque MJ and Marco-Contelles J
Current Topics in Medicinal Chemistry, 17(31), 3349-3360 (2017)
A review on cholinesterase inhibitors for Alzheimer?s disease.
Anand P and Singh B
Archives of Pharmacal Research, 36(4), 375-399 (2013)
Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro.
Ogura H, et al.
Methods and Findings in Experimental and Clinical Pharmacology, 22(8), 609-614 (2000)