C11804
4-Sulfamoylbenzoic acid
97%
동의어(들):
4-Carboxybenzenesulfonamide, Benzoic acid 4-sulfamide
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HO2CC6H4SO2NH2
CAS 번호:
Molecular Weight:
201.20
UNSPSC Code:
12352108
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-327-4
Beilstein/REAXYS Number:
1875393
MDL number:
Assay:
97%
Form:
powder
InChI
1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)
InChI key
UCAGLBKTLXCODC-UHFFFAOYSA-N
SMILES string
O=S(C(C=C1)=CC=C1C(O)=O)(N)=O
assay
97%
form
powder
reaction suitability
reagent type: cross-linking reagent
mp
285-295 °C (lit.)
functional group
carboxylic acid, sulfonamide
Quality Level
Gene Information
human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)
General description
4-Sulfamoylbenzoic acid also known as 4-carboxybenzenesulfonamide, is a sulfonamide derivative of benzoic acid. It is a crosslinking reagent used widely in organic synthesis.
Application
4-Sulfamoylbenzoic acid is used to synthesize 4-sulfamoylbenzoyl chloride and isocyanate derivatives. Additionally, it can be used in the esterification of alcohols.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Jean-Yves Winum et al.
Journal of medicinal chemistry, 48(6), 2121-2125 (2005-03-18)
Targeting proteins overexpressed in hypoxic tumors is as an important means of controlling cancer disease. One such protein is the carbonic anhydrase (CA) isoenzyme IX, which in some types of tumors is overexpressed 150-200-fold. We report here a series of
H C Palfrey et al.
The American journal of physiology, 246(3 Pt 1), C242-C246 (1984-03-01)
The secretory response of isolated perfused shark rectal gland was characterized with respect to its inhibition by a chemically related series of 5-sulfamoylbenzoic acid derivatives and certain phenoxyacetic acid derivatives. Maximal fluid and salt secretion was elicited with dibutyryl adenosine
Tiffani A Greene et al.
PloS one, 6(5), e20123-e20123 (2011-06-02)
Bitter taste stimuli are detected by a diverse family of G protein-coupled receptors (GPCRs) expressed in gustatory cells. Each bitter taste receptor (TAS2R) responds to an array of compounds, many of which are toxic and can be found in nature.
Daniel J Orton et al.
Analytical chemistry, 90(1), 737-744 (2017-11-22)
To better understand disease conditions and environmental perturbations, multiomic studies combining proteomic, lipidomic, and metabolomic analyses are vastly increasing in popularity. In a multiomic study, a single sample is typically extracted in multiple ways, and various analyses are performed using
Daniela Vullo et al.
Bioorganic & medicinal chemistry letters, 15(4), 963-969 (2005-02-03)
The inhibition of a newly cloned human carbonic anhydrase (CA, EC 4.2.1.1), isozyme XII (hCA XII), has been investigated with a series of sulfonamides, including some clinically used derivatives (acetazolamide, methazolamide, ethoxzolamide, dichlorophenamide, dorzolamide, brinzolamide, benzolamide, and sulpiride, or indisulam
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