M1381
4-Methylumbelliferone
≥98%
동의어(들):
β-Methylumbelliferone, 4-MU, 7-Hydroxy-4-methylcoumarin
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C10H8O3
CAS 번호:
Molecular Weight:
176.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-986-7
Beilstein/REAXYS Number:
142217
MDL number:
Assay:
≥98%
Quality Level
assay
≥98%
color
off-white to yellow
fluorescence
λex 372 nm; λem 445 nm in ethanol
SMILES string
CC1=CC(=O)Oc2cc(O)ccc12
InChI
1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3
InChI key
HSHNITRMYYLLCV-UHFFFAOYSA-N
Application
4-Methylumbelliferone is primarily used in synthesizing medicinal compounds and as a building block for fluorescent probes. Applications include synthesis of:
- coumarin triazole derivatives as potential antimicrobial agents.
- coumarin salen-based fluorescence sensors for Mg2+ detection.
- pyranocoumarin derivatives as anti-hyperglycemic and anti-dyslipidemic agents.
- coumarin piperazine derivatives as potential multireceptor atypical antipsychotics.
- 4-methylumbelliferyl T-antigen as a substrate for endo-α-N-acetylgalactosaminidase.
저장 등급
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
Na+ triggered fluorescence sensors for Mg2+ detection based on a coumarin salen moiety.
Dong Y, et al.
Organic Letters, 13(9), 2252-2255 (2011)
Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents.
Shi Y and Zhou C-H
Bioorganic & Medicinal Chemistry Letters, 21(3), 956-960 (2011)
Pyranocoumarins: A new class of anti-hyperglycemic and anti-dyslipidemic agents.
Kumar A, et al.
Bioorganic & Medicinal Chemistry Letters, 19(22), 6447-6451 (2009)
Yutaka Yoshioka et al.
Arthritis and rheumatism, 65(5), 1160-1170 (2013-01-22)
To clarify the roles of hyaluronan (HA) in joint inflammation and the process of joint destruction, using 4-methylumbelliferone (4-MU), an inhibitor of HA synthesis, in a mouse model of collagen-induced arthritis (CIA) and in a monolayer culture of fibroblast-like synoviocytes
Di-tert-butylsilylene-directed α-selective synthesis of 4-methylumbelliferyl T-antigen.
Imamura A, et al.
Organic Letters, 7(20), 4415-4418 (2005)
관련 콘텐츠
Product Information Sheet
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