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Merck

W332208

Thiamine hydrochloride

≥98%, FCC, FG

동의어(들):

Aneurine hydrochloride, Vitamin B1 hydrochloride

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C12H17ClN4OS · HCl
CAS 번호:
Molecular Weight:
337.27
FEMA Number:
3322
Council of Europe no.:
4226
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
16.027
EC Number:
200-641-8
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
3851771
Organoleptic:
sour
Grade:
FG, Halal, Kosher
Biological source:
synthetic
Agency:
meets purity specifications of JECFA
Food allergen:
no known allergens
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도움 문의

biological source

synthetic

Quality Level

grade

FG, Halal, Kosher

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 872/2012, FCC

assay

≥98%

form

powder or crystals

color

white to yellow-white

mp

250 °C (dec.) (lit.)

solubility

H2O: 1 g/10 mL, clear, colorless

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

sour

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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General description

Thiamine hydrochloride is a water-soluble vitamin generally used as a nutrient supplement. When it undergoes heat-degradation, it may form volatile flavor compounds such as hydrogen sulfide, 2-methylthiopehene, 2-methylfuran, and 4,5-dihydro-2-methylthiophene.

Application


  • Construction of hyaluronic acid-functionalized magnolol nanoparticles for ulcerative colitis treatment.: This innovative study explores the synthesis of nanoparticle systems using hyaluronic acid-functionalized magnolol, highlighting thiamine hydrochloride′s role in enhancing therapeutic efficacy and stability in gastrointestinal treatments. This research underlines the biochemical application of thiamine hydrochloride in developing advanced drug delivery systems (Li Y et al., 2024).

  • Constructing Highly Stable Zinc Metal Anodes via Induced Zn(002) Growth.: Investigates the electrochemical stability of zinc anodes, with thiamine hydrochloride playing a critical role in modulating the electrochemical properties and enhancing the anode′s performance, showcasing its potential in next-generation battery technologies (Hu S et al., 2024).

  • Subclinical thiamine deficiency results in failed reproduction in Arctic foxes.: This study identifies the pivotal role of thiamine hydrochloride in preventing reproductive failures linked to nutritional deficiencies in wildlife, extending its application beyond human health to include environmental and conservation aspects (Jackson C et al., 2024).

  • Density Functional Theory and Density Functional Tight Binding Studies of Thiamine Hydrochloride Hydrates.: Highlights computational studies on the molecular structure and stability of thiamine hydrochloride, providing crucial insights into its physicochemical properties and interactions at the molecular level, critical for pharmaceutical formulations (Napiórkowska E et al., 2023).

  • Effects of Nutrients on the Growth of and Free Exopolysaccharide Biosynthesis by Streptococcus thermophilus 937 in a Chemically Defined Medium.: Examines the influence of thiamine hydrochloride among other nutrients on the microbial synthesis processes, underlining its essential role in microbial nutrition and metabolic engineering (Wa Y et al., 2023).

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Validation of HPLC method for determination of thiamine hydrochloride, riboflavin, nicotinamide, and pyridoxine hydrochloride in syrup preparation
Yantih N, et al.
Canadian Journal on Scientific and Industrial Research, 2(7), 269-278 (2011)
Encyclopedia of Food and Color Additives, 1, 2777-2777 null
Spectrophotometric determination of ascorbic acid and thiamine hydrochloride in pharmaceutical products using derivative spectrophotometry
Abdel-Hamid ME, et al.
Analyst, 110(7), 831-835 (1985)
Volatile flavor compounds produced by heat degradation of thiamine (vitamin B1).
Arnold RG, et al.
Journal of Agricultural and Food Chemistry, 17(2), 390-392 (1969)
High-performance liquid chromatography method for the simultaneous determination of thiamine hydrochloride, pyridoxine hydrochloride and cyanocobalamin in pharmaceutical formulations using coulometric electrochemical and ultraviolet detection
Marszall LM, et al.
Journal of Chromatography A, 1094(1-2), 91-98 (2005)

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