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제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
1A6, monoclonal
Species reactivity:
vertebrates
Application:
ICC, IHC, IP, WB
Citations:
127
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1A6, monoclonal
species reactivity
vertebrates
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG2bκ
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NOS1(4842)
General description
Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others
Predicted MW for nitrated-BSA: 66 kDa
Application
Anti-Nitrotyrosine Antibody, clone 1A6 detects level of Nitrotyrosine & has been published & validated for use in IC, IH, IP & WB.
Physical form
Format: Purified
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in 0.014M phosphate buffer, pH 7.6, 0.175M NaCl, 0.07% sodium azide, and 30% glycerol.
Analysis Note
Control
Immunohistochemistry: Human Alzheimer disease brain sections (Methacarn fixed), mouse liver
Immunoblotting: Nitrated-BSA
Indirect ELISA: nitrated-BSA
Indirect immunofluorescence: A549 cells metabolically labeled with 3-nitrotyrosine
Immunohistochemistry: Human Alzheimer disease brain sections (Methacarn fixed), mouse liver
Immunoblotting: Nitrated-BSA
Indirect ELISA: nitrated-BSA
Indirect immunofluorescence: A549 cells metabolically labeled with 3-nitrotyrosine
routinely evaluated on peroxynitrite-treated A431 cells; no reaction was noted with non-nitrated proteins
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Relaxin ameliorates hypertension and increases nitric oxide metabolite excretion in angiotensin II but not N(?)-nitro-L-arginine methyl ester hypertensive rats.
Sasser, JM; Molnar, M; Baylis, C
Hypertension null
Losartan prevents portal hypertension-induced, redox-mediated endothelial dysfunction in the mesenteric artery in rats.
Dal-Ros, Stephanie, et al.
Gastroenterology, 138, 1574-1584 (2010)
Peroxynitrite diminishes myogenic activity and is associated with decreased vascular smooth muscle F-actin in rat posterior cerebral arteries.
Maneen, MJ; Hannah, R; Vitullo, L; DeLance, N; Cipolla, MJ
Stroke null
Biological significance of nitric oxide-mediated protein modifications.
Gow, Andrew J, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 287, L262-L268 (2004)
The extensive nitration of neurofilament light chain in the hippocampus is associated with the cognitive impairment induced by amyloid beta in mice.
Alkam, T; Nitta, A; Mizoguchi, H; Itoh, A; Murai, R; Nagai, T; Yamada, K; Nabeshima, T
Journal of Pharmacology and Experimental Therapeutics null
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 05-233 | 04053252622977 |
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