biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NOTCH4(4855)
General description
68kDa
Immunogen
His-tag fusion protein containing the carboxy-terminus of murine Notch 4
Application
Anti-Notch 4 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of Notch 4 & has been validated in WB.
Biochem/physiol Actions
truncated, intracellular domain of Int3/Notch 4, possibly full-length Notch 4; does not cross-react with Notch 1, 2 or 3
Physical form
Format: Purified
Analysis Note
routinely evaluated by immunoblot on lysates from 293 cells transfected with the intracellular domain of murine Notch 4
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
S Zhang et al.
Oncogene, 35(19), 2485-2495 (2015-08-19)
Notch controls pancreatic differentiation during development and is reactivated in pancreatic cancer. In recent years, the importance of Notch signaling in pancreatic tumorigenesis has become increasingly evident; however, it remains unclear how Notch activities are regulated in this context. Here
Notch4 normalization reduces blood vessel size in arteriovenous malformations.
Murphy, PA; Kim, TN; Lu, G; Bollen, AW; Schaffer, CB; Wang, RA
Science Translational Medicine null
Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer.
Magnani, L; Stoeck, A; Zhang, X; Lanczky, A; Mirabella, AC; Wang, TL; Gyorffy, B; Lupien, M
Proceedings of the National Academy of Sciences of the USA null
Elongin C is a mediator of Notch4 activity in human renal tubule cells.
Cummins, TD; Mendenhall, MD; Lowry, MN; Korte, EA; Barati, MT; Khundmiri, SJ; Salyer et al.
Biochimica et Biophysica Acta null
Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10/Ankyrin repeats.
Sharon Bargo,Ahmed Raafat,David McCurdy,Idean Amirjazil,Youmin Shu,June Traicoff et al.
Biochemical and biophysical research communications null
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| SKU | GTIN |
|---|---|
| 07-189 | 04053252626081 |
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