biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, human, chicken, monkey, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GRIA2(2891)
General description
110 kDa
Immunogen
synthetic peptide corresponding to amino acids 864-883 of rat GluR2
Application
Anti-GluR2/3 Antibody detects level of GluR2/3 & has been published & validated for use in IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurodegenerative Diseases
Neurotransmitters & Receptors
Neurodegenerative Diseases
Biochem/physiol Actions
Recognizes GluR2/3.
Physical form
Format: Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Protein A purified
Preparation Note
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Mouse brain tissue, rat brain microsomal preparation, human brain lysates
Mouse brain tissue, rat brain microsomal preparation, human brain lysates
routinely evaluated by immunoblot on rat brain microsomal preparation (Catalog # 12-144)
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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저장 등급
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Mechanisms of seizure-induced 'transcriptional channelopathy' of hyperpolarization-activated cyclic nucleotide gated (HCN) channels.
Cristina Richichi,Amy L Brewster,Roland A Bender,Timothy A Simeone,Qinqin Zha,Hong Z Yin et al.
Neurobiology of Disease null
A critical role for protein degradation in the nucleus accumbens core in cocaine reward memory.
Ren, ZY; Liu, MM; Xue, YX; Ding, ZB; Xue, LF; Zhai, SD; Lu, L
Neuropsychopharmacology null
Antigenic and mechanistic characterization of anti-AMPA receptor encephalitis.
Gleichman, AJ; Panzer, JA; Baumann, BH; Dalmau, J; Lynch, DR
Annals of Clinical and Translational Neurology null
Diversity of glutamatergic synaptic strength in lateral prefrontal versus primary visual cortices in the rhesus monkey.
Medalla, M; Luebke, JI
The Journal of Neuroscience null
Tommi Möykkynen et al.
The Journal of biological chemistry, 289(19), 13197-13205 (2014-03-22)
AMPA receptors are tetrameric glutamate-gated ion channels that mediate fast synaptic neurotransmission in mammalian brain. Their subunits contain a two-lobed N-terminal domain (NTD) that comprises over 40% of the mature polypeptide. The NTD is not obligatory for the assembly of
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