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Merck

1.02442

Chloroform

for analysis (for determinations with dithizone)

동의어(들):

TCM, Trichloromethane, Methane trichloride, Methyl trichloride, Methylidyne trichloride, Trichloromethane

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
CHCl3
CAS 번호:
Molecular Weight:
119.38
UNSPSC Code:
12191502
NACRES:
NA.21
EC Index Number:
200-663-8
MDL number:
Beilstein/REAXYS Number:
1731042
Assay:
99.0-99.4% (GC)
Vapor pressure:
160 mmHg ( 20 °C)
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vapor density

4.1 (vs air)

Quality Level

vapor pressure

160 mmHg ( 20 °C)

assay

99.0-99.4% (GC)

form

liquid

potency

695 mg/kg LD50, oral (Rat), >3980 mg/kg LD50, skin (Rabbit)

dilution

(for analytical testing)

impurities

≤0.0001% Chloride (Cl), ≤0.001% Free acid (as HCl), ≤0.005% Carbonyl compounds (as CO), ≤0.01% Carbon tetrachloride (GC), ≤0.01% Dichloromethane (GC), ≤0.01% Tetrachloroethylene (GC), ≤0.01% Trichloroethylene (GC), ≤0.01% Water, 0.6-1% Ethanol (GC), 0.6-1.0% Ethanol (GC)

evapn. residue

≤0.001%

mp

−63 °C (lit.)

cation traces

Al: ≤0.00005%, B: ≤0.000002%, Ba: ≤0.00001%, Ca: ≤0.00005%, Cd: ≤0.000005%, Co: ≤0.000002%, Cr: ≤0.000002%, Cu: ≤0.000002%, Fe: ≤0.00001%, Mg: ≤0.00001%, Mn: ≤0.000002%, Ni: ≤0.000002%, Pb: ≤0.00001%, Sn: ≤0.00001%, Zn: ≤0.00001%

storage temp.

2-30°C

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

Application


  • Characterization of Natural Products: Chloroform is extensively used in the extraction and isolation of natural products. A study on the characterization and pesticidal evaluation of diterpenes isolated from chloroform extracts of Hedychium spicatum rhizomes highlights its effectiveness. This application is crucial for identifying bioactive compounds and assessing their potential uses in pharmaceuticals and agrochemicals (Rawat et al., Analytical Chemistry Letters, 2023).

  • Self-Diffusion and Molecular Association Studies: Chloroform is used in studies of self-diffusion and molecular association in binary systems, such as dimethyl sulfoxide (DMSO) and acetone. These studies provide insights into the molecular interactions and dynamics in mixed solvents, which are essential for understanding solvation and reaction mechanisms in various chemical processes (Gurina and Golubev, Results in Chemistry, 2022).

  • Cell-Free DNA Isolation: A novel phenol-chloroform-free method for isolating cell-free DNA from cell-conditioned media has been developed, optimized, and compared with traditional methods. This advancement is significant for genomic studies, allowing for more efficient and less hazardous extraction of nucleic acids from biological samples (Das et al., Analytical Biochemistry, 2024).

  • Green Chemistry and Circular Economy: Chloroform plays a role in green analytical chemistry, particularly in the development of circular chemistry principles. Research emphasizes the need to design chemical processes that minimize waste and environmental impact, promoting sustainability in analytical laboratories. This includes the use of chloroform in recyclable and reusable systems to reduce solvent waste (Psillakis and Pena-Pereira, TrAC Trends in Analytical Chemistry, 2024).

Other Notes

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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

target_organs

Central nervous system, Liver,Kidney

저장 등급

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects



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국제 무역 품목 번호

SKUGTIN
1.02442.100004022536033501
1.02442.250004022536033525