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Merck

1.52321

Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns

L × I.D. 50 mm × 2 mm HPLC Column

동의어(들):

Chromolith® HighResolution RP-18 endcapped 50-2 HPLC column

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UNSPSC Code:
41115709
NACRES:
SB.52
Matrix active group:
C18 (RP18), C18 bonding phase, octadecylsilane (ODS)
Pore size:
1.5 μm macroporosity, 15 nm mesoporosity
Matrix:
highly porous, monolithic silica
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제품 이름

Chromolith® HighResolution RP-18 endcapped, L × I.D. 50 mm × 2 mm HPLC column

Quality Segment

feature

endcapped

extent of labeling

18% Carbon loading

parameter

200 bar pressure, 50 °C max. temp.

technique(s)

HPLC: suitable, mass spectrometry (MS): suitable (High)

column L × I.D.

50 mm × 2 mm

surface area

250 m2/g

matrix

highly porous, monolithic silica

matrix active group

C18 (RP18), C18 bonding phase, octadecylsilane (ODS)

pore size

1.5 μm macroporosity, 15 nm mesoporosity

operating pH range

2-7.5

General description

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® HighResolution RP-18 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), and the surface modification is octadecylsilane with full end-capping. Chromolith® HighResolution RP-18 endcapped columns fall under the USP L1 Classification. The column efficiency is comparable to a 2.7 to 3 μm particle size fully porous particulate column.
The column dimension of 50 mm length and 2 mm I.D. is the best choice for fast and high-resolution separations meeting UHPLC and LC-MS needs.

Chromolith® HighResolution RP-18 endcapped columns with 2 mm internal diameter are ideal for use with UHPLC or UPLC instruments, thanks to their very small internal volumes. A particular benefit is very fast analysis, reduced sample preparation and the low column backpressure. Ultra-high performance and extremely low operating pressure make Chromolith® 2 mm I.D. columns truly unique. Chromolith® and Chromolith® HighResolution columns are perfectly suitable for LC-MS use; however, the column dimension of 2 mm I.D. or below is preferred to be used in LC-MS methods.

The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes
—Connection of columns, flow gradients and the use of mobile phases with higher viscosity

The recommended Guard-columns are:
Chromolith® HighResolution RP-18 endcapped 5-2 guard cartridges (3 pieces) [1.52325] with the Chromolith® Guard Cartridge Holder 5 mm x 2 mm [1.52355]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

Flyer: UHPLC-like performance - Rapid and Robust at Low Pressure - Chromolith® HighResolution RP-18 endcapped 2 mm I.D. HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany


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