biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
bovine, mouse, rat
should not react with
canine
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
bovine ... Hmox1(513221)
dog ... Hmox1(442987)
mouse ... Hmox1(15368)
rat ... Hmox1(24451)
General description
32 kDa
Immunogen
A synthetic peptide with the amino acid sequence H-D-L-S-E-A-L-K-E-A-T-K-E-V-H-C-NH2 corresponding to amino acid residues [12-25] + Cys-NH2 of the human HO-1 protein (Yoshida et al., 1988).
Application
Research Category
Metabolism
Metabolism
Research Sub Category
Toxicology & Drug Resistance
Toxicology & Drug Resistance
This Anti-Heme Oxygenase 1 Antibody is validated for use in IH, WB for the detection of Heme Oxygenase 1.
Western Blot: 1:1,000 (using ECL). A single band of ~32 kD is observed. Reactivity can be completely abolished by pre-adsorption of the antibody with the complementary peptide (Catalog Number AG253). Also available are microsomal tissue preparations for control purposes (Rat spleen microsomal preparation, Catalog Number AG257).
Immunohistochemistry: 1:50-1:1,000 on human airway biopsy, human spleen, human kidney and porcine arteries.
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:50-1:1,000 on human airway biopsy, human spleen, human kidney and porcine arteries.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes Heme oxygenase-1.
Physical form
Affinity Purified immunoglobulin. Liquid in PBS containing 0.01M sodium azide.
ImmunoAffinity Purified
Preparation Note
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Lung
Lung
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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당사의 제품 선택기 도구.을(를) 시도해 보세요.
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
저장 등급
12 - Non Combustible Liquids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Resveratrol increases vascular oxidative stress resistance.
Ungvari, Z; Orosz, Z; Rivera, A; Labinskyy, N; Xiangmin, Z; Olson, S; Podlutsky, A; Csiszar, A
American Journal of Physiology. Heart and Circulatory Physiology null
Heme oxygenase-1 could mediate the protective effects of hyperbaric oxygen preconditioning against hepatic ischemia-reperfusion injury in rats.
Yi Liu,Xue-Jun Sun,Ji Liu,Zhi-Min Kang,Xiao-Ming Deng
Clinical and Experimental Pharmacology & Physiology null
Purification and properties of heme oxygenase from pig spleen microsomes
Yoshida T, and Kikuchi G.
The Journal of Biological Chemistry, 253, 4224-4229 (1978)
Solubilization and partial purification of heme oxygenase from rat liver.
Maines, M D, et al.
The Journal of Biological Chemistry, 252, 5900-5903 (1977)
Up-regulation of heme oxygenase-1 by isoflurane preconditioning during tolerance against neuronal injury induced by oxygen glucose deprivation.
Qifang Li, Yesen Zhu, Hong Jiang, Hui Xu, Heping Liu
Acta biochimica et biophysica Sinica null
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| AB1284 | 04053252670510 |
| AG253 | 04053252279089 |
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