biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
bovine, guinea pig, rat, human, feline, rabbit
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, radioimmunoassay: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... DBH(1621)
General description
69 kDa
Immunogen
Native enzyme from bovine adrenal glands.
Application
Detect Dopamine β Hydroxylase using this Anti-Dopamine β Hydroxylase Antibody validated for use in IH, FUNC, RIA & WB.
Immunohistochemistry: 1:2,000 on rabbit and guinea pig using an ABC detection method.
Western blot
RIA
Inhibitory studies in vivo and in vitro.
Optimal working dilutions must be determined by the end user.
Western blot
RIA
Inhibitory studies in vivo and in vitro.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neuronal & Glial Markers
Neurotransmitters & Receptors
Neuronal & Glial Markers
Biochem/physiol Actions
Recognizes Dopamine beta hydroxylase. AB1585 reacts with a single band on Western blots of bovine adrenal homogenates and stains only cells known to contain DBH, such as sympathetic neurons, adrenal medullary cells and central adrenergic neurons. Staining is abolished by preincubation with enzyme.
Physical form
Rabbit Serum. Lyophilized, no preservatives. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material.
Unpurified
Preparation Note
Maintain lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20 to -70°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles. Glycerol can be added 1:1 for additional stability.
Analysis Note
Control
Brain (Striatum/Substantia Nigra)
Brain (Striatum/Substantia Nigra)
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: AB145
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The toxicity of tumor necrosis factor-alpha upon cholinergic neurons within the nucleus basalis and the role of norepinephrine in the regulation of inflammation: implications for Alzheimer's disease.
Wenk, GL; McGann, K; Hauss-Wegrzyniak, B; Rosi, S
Neuroscience null
Sex and species differences in tyrosine hydroxylase-synthesizing cells of the rodent olfactory extended amygdala.
Katharine V Northcutt, Zuoxin Wang, Joseph S Lonstein
The Journal of Comparative Neurology null
Characteristics of the trigeminal depressor response in cats
Ohshita, N. et al.
Journal of Neuroscience Research, 76(6), 891-901 (2004)
Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons.
Hook, V; Brennand, KJ; Kim, Y; Toneff, T; Funkelstein, L; Lee, KC; Ziegler, M; Gage, FH
Stem Cell Reports null
Jimena Baleriola et al.
Scientific reports, 6, 25928-25928 (2016-05-14)
Programmed cell death occurs naturally at different stages of neural development, including neurogenesis. The functional role of this early phase of neural cell death, which affects recently differentiated neurons among other cell types, remains undefined. Some mouse models defective in
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| AB1585 | 04053252732089 |
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