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Merck

MAB1567

Anti-Myelin Associated Glycoprotein Antibody, clone 513

clone 513, Chemicon®, from mouse

동의어(들):

MAG

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
513, monoclonal
Application:
ICC, IHC, WB
Citations:
96
기술 서비스
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도움 문의

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

513, monoclonal

species reactivity

mouse, rat, frog, bovine, chicken, human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... MAG(4099)

General description

100 kDa
Myelin-associated glycoprotein (MAG),a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.

Immunogen

L2 epitope carrying glycoprotein extract of 1-2 day old chicken brain.

Application

Detect Myelin Associated Glycoprotein using this Anti-Myelin Associated Glycoprotein Antibody, clone 513 validated for use in IC, IH & WB.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurochemistry & Neurotrophins
Western Blot:
20 μg/mL of a previous lot was used on western blot under non-reducing conditions only.{See Ellezam, 2003}

Immunocytochemistry:
5-10 µg/mL of a previous lot was used, methanol fixation required.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Detects Myelin Associated Glycoprotein (MAG) in immunohistochemistry on frozen sections, immunocytochemistry and Western blot (under non-reducing conditions). MAB1567 is useful for myelinogenesis and multiple sclerosis studies.

Physical form

Format: Purified
Protein A purified
Purified mouse monoclonal IgG1 in buffer containing 10 mM potassium phosphate buffer, 50 mM NaCl, pH 7.5. Contains no preservative.

Preparation Note

Stable for 1 year at -20ºC from date of receipt.

Analysis Note

Control
Rat hippocampus tissue, rat brain lysate, PC12 cells.
Evaluated by immunohistochemistry on rat hippocampus.

Immunohistochemistry(paraffin):
Representative image from a previous lot.
Mouse anti-Myelin Associated Glycoprotein [MAG] (Catalog Number MAB1567) localization of MAG in rat hippocampus. Photo courtesy of Dr. Robert Sloviter, University of Arizona.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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저장 등급

10 - Combustible liquids

wgk

WGK 2


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Infection of stationary human brain aggregates with HIV-1 SF162 and IIIB results in transient neuronal damage and neurotoxicity.
Trillo-Pazos, G, et al.
Neuropathology and Applied Neurobiology, 30, 136-147 (2004)
Myelin-associated glycoprotein reduces axonal branching and enhances functional recovery after sciatic nerve transection in rats.
Koichi Tomita,Tateki Kubo,Ken Matsuda,Kenji Yano,Masaya Tohyama,Ko Hosokawa
Glia null
Connexin29 expression, immunocytochemistry and freeze-fracture replica immunogold labelling (FRIL) in sciatic nerve.
Xinbo Li, B D Lynn, C Olson, C Meier, K G V Davidson, T Yasumura, J E Rash, J I Nagy
The European Journal of Neuroscience null
Myelin-associated glycoprotein interacts with ganglioside GT1b. A mechanism for neurite outgrowth inhibition.
Vinson, M; Strijbos, PJ; Rowles, A; Facci, L; Moore, SE; Simmons, DL; Walsh, FS
The Journal of Biological Chemistry null
A Görlich et al.
Neuroscience, 168(2), 564-572 (2010-04-17)
One strategy in localizing a sound source in the azimuthal plane is the comparison of arrival times of sound stimuli at the two ears. The processing of interaural time differences (ITDs) in the auditory brainstem was suggested by the Jeffress

국제 무역 품목 번호

SKUGTIN
MAB156704053252359828

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