MAB3402

Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5

Name: Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5
Brand: MM

clone GA5, Chemicon^®, from mouse

동의어(들):

GFAP

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

GA5, monoclonal

Application:

ICC, IHC (p), WB

Citations:

389

주요 문서

모든 문서 보기

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

GA5, monoclonal

species reactivity

chicken, pig, rat, bovine, mouse, rabbit, human

manufacturer/tradename

Chemicon^®

technique(s)

immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable

isotype

IgG1

UniProt accession no.

F1RR02

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GFAP(2670)

General description

50 kDa

Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.

Immunogen

Purified Glial Fibrillary Acidic Protein (GFAP) from pig spinal cord (Debus, E., 1983).

Application

Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5 is an antibody against Glial Fibrillary Acidic Protein for use in IC, IH, IH(P) & WB with more than 55 product citations.

Immunocytochemistry:
5 μg/mL of a previous lot was used.

Immunohistochemistry:
5 µg/mL

Immunoblotting:
Recognizes a 51kDa protein in reducing westerns of total brain lysates.

Optimal working dilutions must be determined by end user.

Research Category
Neuroscience

Research Sub Category
Neuronal & Glial Markers

Biochem/physiol Actions

Expected to cross-react with porcine, chicken, bovine, and rabbit.

The antibody reacts with GFAP from human, pig, chicken and rat. In tissue sections this antibody stains astrocytes and Bergman glia cells (Debus, E., 1983).

Physical form

Format: Purified

Protein A purified

Purified mouse monoclonal IgG1 in buffer containing 0.02 M phosphate buffer, 0.25 M NaCl with 0.1% sodium azide, pH 7.6.

Preparation Note

Store the reconstituted antibody at 2-8°C for up to 6 months after date of receipt.
DO NOT FREEZE.

Analysis Note

Control
Mouse brain tissue, Astrocyte culture.

Routinely evaluated by Western Blot on Mouse brain lysate.

Western Blot Analysis:
1:1000 dilution of this lot detected Glial Fibrillary Acidic Protein on 10 μg of Mouse Brain lysate.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Replaces: 04-1031; 04-1062

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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저장 등급

10 - Combustible liquids

wgk

WGK 2

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Evidence for catabolic pathway of propionate metabolism in CNS: expression pattern of methylmalonyl-CoA mutase and propionyl-CoA carboxylase alpha-subunit in developing and adult rat brain.

D Ballhausen et al.

Neuroscience, 164(2), 578-587 (2009-08-25)

Methylmalonyl-CoA mutase (MCM) and propionyl-CoA carboxylase (PCC) are the key enzymes of the catabolic pathway of propionate metabolism and are mainly expressed in liver, kidney and heart. Deficiency of these enzymes leads to two classical organic acidurias: methylmalonic and propionic

Proliferation inhibition, DNA damage, and cell-cycle arrest of human astrocytoma cells after acrylamide exposure.

Chen JH, Tsou TC, Chiu IM, Chou CC

Chemical Research in Toxicology null

Alteration of glial-neuronal metabolic interactions in a mouse model of Alexander disease.

Meisingset, TW; Risa, ?; Brenner, M; Messing, A; Sonnewald, U

Glia null

Tenascin-C regulates proliferation and migration of cultured astrocytes in a scratch wound assay.

T Nishio et al.

Neuroscience, 132(1), 87-102 (2005-03-23)

Tenascin-C (TNC), an extracellular matrix glycoprotein, is involved in tissue morphogenesis like embryogenesis, wound healing or tumorigenesis. Astrocytes are known to play major roles in wound healing in the CNS. To elucidate the roles of TNC in wound closure by

Selective removal of photoreceptor cells in vivo using the biodegradable elastomer poly(glycerol sebacate).

Ghosh, F; Neeley, WL; Arner, K; Langer, R

Tissue Engineering: Part A null

모든 관련된 서류 보기

문서

Derivation of Functional Oligodendrocyte Progenitor Cells (OPCs) from Human Neural Stem Cell Lines

Derivation and characterization of functional human neural stem cell derived oligodendrocyte progenitor cells (OPCs) that efficiently myelinate primary neurons in culture.

Robust Differentiation of Human iPSCs into Lineage-Specific Neurons and Glial Cells Utilizing Dual-SMAD Inhibition

Human iPSC neural differentiation media and protocols used to generate neural stem cells, neurons and glial cell types.

국제 무역 품목 번호

SKU	GTIN
MAB3402	08436037122521

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.

Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5

clone GA5, Chemicon®, from mouse

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

biological source

Quality Level

conjugate

antibody form

antibody product type

clone

species reactivity

manufacturer/tradename

technique(s)

isotype

UniProt accession no.

shipped in

target post-translational modification

Gene Information

관련 카테고리

설명

General description

Immunogen

Application

Biochem/physiol Actions

Physical form

Preparation Note

Analysis Note

Other Notes

Legal Information

Disclaimer

안전성 정보

저장 등급

wgk

문서

시험 성적서(COA)

이 제품을 이미 가지고 계십니까?

관련 참고 논문

관련 참고 프로토콜

문서

관련 콘텐츠

국제 무역 품목 번호

기술 서비스

clone GA5, Chemicon^®, from mouse