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Merck

11569

3,4-Dihydroxyphenylacetic acid

analytical standard

동의어(들):

DOPAC, Homoprotocatechuic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(HO)2C6H3CH2CO2H
CAS 번호:
Molecular Weight:
168.15
UNSPSC Code:
77101502
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-024-1
Beilstein/REAXYS Number:
2211017
MDL number:
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InChI

1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)

InChI key

CFFZDZCDUFSOFZ-UHFFFAOYSA-N

SMILES string

OC(=O)Cc1ccc(O)c(O)c1

grade

analytical standard

assay

≥97.0% (HPLC), 97.0-103.0% (T)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

127-130 °C (lit.)

application(s)

pharmaceutical

format

neat

Quality Level

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Application

3,4-Dihydroxyphenylacetic acid may be used as a reference standard for the determination of 3,4-dihydroxyphenylacetic acid in rat samples by high-performance liquid chromatography with electrochemical detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Simultaneous determination of 3, 4?dihydroxyphenylalanine, 5?hydroxytryptophan, dopamine, 4?hydroxy?3?methoxyphenylalanine, norepinephrine, 3, 4?dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5?hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high?performance liquid chromatography with electrochemical detection.
Wagner J, et al.
Journal of Neurochemistry, 38(5), 1241-1254 (1982)
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Biomolecules & therapeutics, 28(3), 282-291 (2020-04-28)
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Journal of neurochemistry, 150(3), 282-295 (2019-05-24)
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Sandy Stayte et al.
PloS one, 10(4), e0124325-e0124325 (2015-04-23)
Parkinson's disease (PD) is a chronic neurodegenerative disease characterized by a significant loss of dopaminergic neurons within the substantia nigra pars compacta (SNpc) and a subsequent loss of dopamine (DA) within the striatum. Despite advances in the development of pharmacological
Bing Han et al.
Parkinsonism & related disorders, 20(11), 1191-1195 (2014-09-16)
Parkinson's disease (PD) is a progressive neurodegenerative movement disorder that is caused predominantly by the degeneration of the nigrostriatal dopaminergic pathway. Lateral habenula (LHb) has efferent projections that terminate in the substantia nigra pars compacta (SNpc) and electrical stimulation of

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