15522
D-(+)-Galactose
meets analytical specification of Ph. Eur., BP
동의어(들):
Galactose
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C6H12O6
CAS 번호:
Molecular Weight:
180.16
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-416-4
Beilstein/REAXYS Number:
1724619
MDL number:
form
powder
quality
meets analytical specification of Ph. Eur., BP
technique(s)
IR spectroscopy: suitable
impurities
acid. or alk. react. impurities, in accordance, microbiological impurity, in accordance, residual solvents, in accordance, ≤1.0% water (Karl Fischer)
color
white
useful pH range
5.0-7.0 (25 °C, 180 g/L)
Quality Level
InChI key
GZCGUPFRVQAUEE-KCDKBNATSA-N
InChI
1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1
SMILES string
OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
mp
168-170 °C (lit.)
solubility
H2O: soluble 180 g/L at 20 °C
suitability
in accordance for appearance of solution, in accordance for identity (IR)
application(s)
pharmaceutical (small molecule)
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Application
D-(+)-Galactose was used for examining the specificity of staining with SBA-FITC during labeling of cells for fluorescence-activated cell sorting (FACS). It was used for selecting the transformed strains of S. cerevisiae.
Biochem/physiol Actions
Galactose is a monosaccharide sugar and is the natural antigen present on the blood cells. It induces memory loss, neurodegeneration as well as oxidative damage in mice due to systemic exposure.
Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Elizabeth M Prescott et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(13), 8796-8801 (2002-06-22)
Transcriptional interference between genes and the regulatory elements of simple eukaryotes such as Saccharomyces cerevisiae is an unavoidable consequence of their compressed genetic arrangement. We have shown previously that with the tandem arranged genes GAL10 and GAL7, inefficient transcriptional termination
Xu Cui et al.
Journal of neuroscience research, 84(3), 647-654 (2006-05-20)
Chronic systemic exposure of mice, rats, and Drosophila to D-galactose causes the acceleration of senescence and has been used as an aging model. The underlying mechanism is yet unclear. To investigate the mechanisms of neurodegeneration in this model, we studied
P J Simmons et al.
Blood, 78(11), 2848-2853 (1991-12-01)
Normal bone marrow cells were isolated by fluorescence-activated cell sorting (FACS) on the basis of CD34 antigen expression and then assayed in vitro for colonies of fibroblastic cells (fibroblast colony-forming units [CFU-F]). Greater than 95% of detectable CFU-F were recovered
L Mortimer et al.
Mucosal immunology, 7(4), 829-841 (2013-11-21)
Entamoeba histolytica (Eh) is an extracellular protozoan parasite of the human colon, which occasionally breaches the intestinal barrier. Eradicating ameba that invades is essential for host survival. A defining but uncharacterized feature of amebic invasion is direct contact between ameba
Cheryl M Koh et al.
The Journal of clinical investigation, 125(5), 2109-2122 (2015-04-22)
Constitutively active MYC and reactivated telomerase often coexist in cancers. While reactivation of telomerase is thought to be essential for replicative immortality, MYC, in conjunction with cofactors, confers several growth advantages to cancer cells. It is known that the reactivation
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