42147
(RS)-Mevalonic acid lithium salt
analytical standard
동의어(들):
(±)-MVA-Li, rac.-MVA-Li, Lithium (±)-3,5-dihydroxy-3-methyl-pentanoate, Lithium (±)-3,5-dihydroxy-3-methyl-valerate
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C6H11O4 · xLi+
CAS 번호:
Molecular Weight:
147.15 (free acid basis)
MDL number:
UNSPSC Code:
85151701
NACRES:
NA.24
grade
analytical standard
Quality Level
assay
≥96.0% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
SMILES string
OC(CCO)(CC(=O)O)C
InChI
1S/C6H12O4/c1-6(10,2-3-7)4-5(8)9/h7,10H,2-4H2,1H3,(H,8,9)
InChI key
KJTLQQUUPVSXIM-UHFFFAOYSA-N
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Analysis Note
NMR-Internal standard: Dimethylsulfone
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Jinbo Gao et al.
Biochimica et biophysica acta, 1830(6), 3635-3642 (2013-02-23)
Mevalonate pathway is an important cellular metabolic pathway present in all higher eukaryotes and many bacteria. Four enzymes in mevalonate pathway, including MVK, PMK, MDD, and FPPS, play important regulatory roles in cholesterol biosynthesis and cell proliferation. The following methods
Jesus A Villanueva et al.
The Journal of clinical endocrinology and metabolism, 98(3), E455-E462 (2013-02-07)
Growth of endometriotic lesions in rodent model of endometriosis is inhibited by resveratrol, a natural polyphenol with antiproliferative and antiinflammatory properties, and simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) activity. The objective of the investigation was to study the
James J DiNicolantonio
Expert review of cardiovascular therapy, 10(10), 1329-1333 (2012-11-30)
Statins are a standard of care in many clinical settings such as acute myocardial infarction and for patients having or at risk of cardiovascular (CV) disease. This is based on a plethora of data showing reductions in CV events and