73177
1-Fluoro-2,4-dinitrobenzene
derivatization grade (HPLC), LiChropur™, ≥99.0% (GC)
동의어(들):
2,4-Dinitro-1-fluorobenzene, DNFB, DNPF, FDNB, Sanger reagent
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(O2N)2C6H3F
CAS 번호:
Molecular Weight:
186.10
UNSPSC Code:
23151817
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-734-3
Beilstein/REAXYS Number:
398632
MDL number:
Assay:
≥99.0% (GC)
Form:
(Solid or Semi-Solid or Chunk(s) or Paste or Liquid)
InChI
1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H
InChI key
LOTKRQAVGJMPNV-UHFFFAOYSA-N
SMILES string
[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O
grade
derivatization grade (HPLC)
assay
≥99.0% (GC)
form
(Solid or Semi-Solid or Chunk(s) or Paste or Liquid)
quality
LiChropur™
technique(s)
HPLC: suitable
color
light yellow to very dark green-yellow, and Light Green to Very Dark Green
Quality Level
bp
178 °C/25 mmHg (lit.)
density
1.482 g/mL at 25 °C (lit.)
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General description
1-Fluoro-2,4-dinitrobenzene is a color labeling agent, mainly used for detecting primary and secondary amines.
Application
1-Fluoro-2,4-dinitrobenzene may be used as a derivatizing reagent for the determination of gabapentin in human plasma samples, pharmaceutical formulations and memantine hydrochloride in pharmaceutical formulations using high-performance liquid chromatography technique.
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
10 - Combustible liquids
wgk
WGK 3
flash_point_f
327.2 °F
flash_point_c
164 °C
A stability-indicating HPLC method for the determination of memantine hydrochloride in dosage forms through derivatization with 1-fluoro-2, 4-dinitrobenzene
Jalalizadeh H, et al.
Scientia Pharmaceutica, 82(2), 265-280 (2014)
Morten M Nielsen et al.
Journal of immunology (Baltimore, Md. : 1950), 192(7), 2975-2983 (2014-03-07)
Substances that penetrate the skin surface can act as allergens and induce a T cell-mediated inflammatory skin disease called contact hypersensitivity (CHS). IL-17 is a key cytokine in CHS and was originally thought to be produced solely by CD4(+) T
Otgonzaya Ayush et al.
The Journal of investigative dermatology, 133(3), 723-731 (2012-10-19)
L-glutamine (Gln) is a nonessential amino acid that is the most abundant amino acid in plasma. Gln has been reported to have an anti-inflammatory activity that involves deactivation of mitogen-activated protein kinases (MAPKs) in a MAPK phosphatase (MKP)-1-dependent manner. This
Sonia Schuepbach-Mallepell et al.
The Journal of allergy and clinical immunology, 132(6), 1348-1357 (2013-08-21)
Innate immune sensors control key cytokines that regulate T-cell priming and T-cell fate. This is particularly evident in allergic reactions, which represent ideal systems to study the interplay of innate and adaptive immunity. In patients with contact dermatitis, inflammasome-mediated IL-1
Helena Shifrin et al.
PloS one, 8(2), e57668-e57668 (2013-03-08)
The cholinergic anti-inflammatory system and α7 nicotinic receptors in macrophages have been proposed to play a role in neuroimmunomodulation and in the etiology of ulcerative colitis. We investigated the ability of a cholinesterase (ChE) inhibitor rivastigmine, to improve the pathology
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