81242
Poly(ethylene glycol)
tested according to Ph. Eur., 4,000
동의어(들):
Macrogol 4,000, Polyethylene glycol, PEG
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
H(OCH2CH2)nOH
CAS 번호:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
agency
tested according to Ph. Eur.
form
solid
mol wt
3500-4500
greener alternative product characteristics
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
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application(s)
pharmaceutical (small molecule)
greener alternative category
Quality Level
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General description
Poly(ethylene glycol) (PEG) is a non-toxic water-soluble polymer. PEG term is used for the polymer chains with molecular weights below 20 000, while poly(ethylene oxide) (PEO) refers to the higher molecular weight polymers. PEG has various biomedical applications. It forms complexes with α-cyclodextrins. Engineering of PEG hydrogel particles by mesoporous silica (MS) templating method has been reported.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
Application
Poly(ethylene glycol) may be used in the following studies:
- For the modification of proteins to form the conjugates having increased circulating life and reduced immunogenicity and antigenicity.
- Preparation of hydrogels useful for the diffusion controlled delivery of proteins.
- Preparation of poly(ethylene glycol) dimethacrylate (PEGDM).
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
The clinical efficacy of poly (ethylene glycol)-modified proteins.
Fuertges F and Abuchowski A.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 11(1), 139-148 (1990)
N A Peppas et al.
Journal of controlled release : official journal of the Controlled Release Society, 62(1-2), 81-87 (1999-10-16)
The use of hydrogels as carriers for protein delivery has been a subject of significant recent research. In our recent work, we have shown that diffusion controlled delivery of proteins from hydrogels containing poly(ethylene glycol) (PEG) can be possible and
Stephanie J Bryant et al.
Annals of biomedical engineering, 32(3), 407-417 (2004-04-21)
In approaches to tissue engineer articular cartilage, an important consideration for in situ forming cell carriers is the impact of mechanical loading on the cell composite structure and function. Photopolymerized hydrogel scaffolds based on poly(ethylene glycol) (PEG) may be synthesized
Complex formation between poly (ethylene glycol) and α-cyclodextrin.
Harada A and Kamachi M.
Macromolecules, 23(10), 2821-2823 (1990)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
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