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Merck

91230

Trichloroacetic acid

ACS reagent grade, ≥99.5% (T), flakes, for the determination of Fe in blood according to Heilmeyer

동의어(들):

TCA

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
Cl3CCOOH
CAS 번호:
Molecular Weight:
163.39
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-927-2
MDL number:
Beilstein/REAXYS Number:
970119
Assay:
≥99.5% (T), ≥99.5%
Form:
flakes
Grade:
ACS reagent
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제품 이름

Trichloroacetic acid, ACS reagent, for the determination of Fe in blood according to Heilmeyer, ≥99.5%

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

SMILES string

OC(=O)C(Cl)(Cl)Cl

grade

ACS reagent

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)

assay

≥99.5% (T), ≥99.5%

form

flakes

quality

for the determination of Fe in blood according to Heilmeyer

ign. residue

≤0.03% (as SO4)

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubility

water: soluble 81.7 g/L at 20 °C

density

1.62 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤10 mg/kg, nitrate (NO3-): ≤20 mg/kg, phosphate (PO43-): ≤5 mg/kg, sulfate (SO42-): ≤200 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

functional group

carboxylic acid, chloro

Quality Level

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General description

Trichloroacetic acid (TCA) is a chlorinated acetic acid. It is one of the major metabolites of trichloroethylene (TCE).

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Trichloroacetic acid may be used in the following studies:
  • Estimation of phosphorus in various biological samples (serum, urine and stool ash solutions).
  • Elimination of acid-soluble and lipid phosphorous during the determination of deoxyribonucleic acid, ribonucleic acid and phosphoproteins in animal tissues.
  • Preparation of 2-methyl-4-nitroanilinium trichloroacetate trichloroacetic acid (2M4NATCA) crystals.

10% Trichloroacetic acid may be employed for the preparation of radioactive proteins.

Other Notes

Protein denaturant.

pictograms

CorrosionEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

저장 등급

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Protein assay for dilute solutions.
E Cabib et al.
Methods in enzymology, 104, 415-416 (1984-01-01)
A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues.
G SCHMIDT et al.
The Journal of biological chemistry, 161, 83-89 (1945-01-01)
Solubility of albumin in alcohol after precipitation by trichloroacetic acid: a simplified procedure for separation of albumin.
J R DEBRO et al.
Nature, 178(4541), 1067-1067 (1956-11-10)
A microcolorimetric method for the determination of inorganic phosphorus.
H H TAUSSKY et al.
The Journal of biological chemistry, 202(2), 675-685 (1953-06-01)
S L Herren-Freund et al.
Toxicology and applied pharmacology, 90(2), 183-189 (1987-09-15)
Trichloroethylene (TCE) has previously been shown to be carcinogenic in mouse liver when administered by daily gavage in corn oil. The metabolism of TCE results, in part, in the formation of trichloroacetic acid (TCA) as a major metabolite and dichloroacetic

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