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Merck

A7085

Acetaminophen

BioXtra, ≥99.0%

동의어(들):

4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
CH3CONHC6H4OH
CAS 번호:
103-90-2
Molecular Weight:
151.16
UNSPSC Code:
12352111
NACRES:
NA.25
PubChem Substance ID:
24891173
EC Number:
203-157-5
Beilstein/REAXYS Number:
2208089
MDL number:
MFCD00002328
Assay:
≥99.0%
Form:
powder

주요 문서

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InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

SMILES string

CC(=O)Nc1ccc(O)cc1

product line

BioXtra

assay

≥99.0%

form

powder

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

Quality Level

200

Gene Information

human ... FAAH(2166), PTGS1(5742), PTGS2(5743), TRPV1(7442)

solubility

ethanol: 0.5 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%, sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

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관련 카테고리

General description

Acetaminophen or paracetamol is an analgesic and antipyretic. It is however a weak non opioid analgesic.

Application

Acetaminophen has been used:
  • as an anti-inflammatory drug to test its effect in lipid peroxidation in marine mussels
  • to test its effect on neurite outgrowth in gamma-aminobutyric acid-ergic and glutamatergic neurons
  • as a hepatocellular injury inducing agent in mice

Analgesic.

Biochem/physiol Actions

Acetaminophen or paracetamol is an inhibitor of prostaglandin synthesis. It is complexed with arachidonic acid in central nervous system resulting in the formation of N-arachidonoylphentolamine, which is essential for the activation of cannabinoid receptor. Acetaminophen is metabolized to toxic N-acetyl-p-benzoquinone imine. Paracetamol is prescribed for osteoarthritis pain and inhibits cyclooxygenase 1 and 2 activities. It is metabolized by the cytochrome P450 enzymes in liver and is implicated in liver toxicity.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

364.3 °F - Pensky-Martens closed cup

flash_point_c

184.6 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
SLCF8273
SLCB2770
SLBV7784
SLBR2060V
SLBM5923V

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Early detection of acute druginduced liver injury in mice by non-invasive NIR fluorescence imaging
Vasquez KO and Peterson JD
Journal of Pharmacology and Experimental Therapeutics, 1(4), 23-23 (2017)
Effects on feeding rate and biomarker responses of marine mussels experimentally exposed to propranolol and acetaminophen
Sole M, et al.
Analytical and Bioanalytical Chemistry, 396(2), 649-656 (2010)
Raphaël F-X Tomasi et al.
Cell reports, 31(8), 107670-107670 (2020-05-28)
As three-dimensional cell culture formats gain in popularity, there emerges a need for tools that produce vast amounts of data on individual cells within the spheroids or organoids. Here, we present a microfluidic platform that provides access to such data
Interactions between Acetaminophen and Phytotherapies: Overview for the Rational Use of Phytotherapics
Ribeiro J, et al.
Journal of Natural Product and Plant Resources, 8(3), 1-14 (2018)
Paracetamol: mechanisms and updates
Sharma CV and Mehta V
Continuing education in anaesthesia, critical care & pain, 14(4), 153-158 (2013)
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