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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(C2H5)2NCSS2CSN(C2H5)2
CAS 번호:
Molecular Weight:
296.54
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
202-607-8
Beilstein/REAXYS Number:
1712560
MDL number:
grade
pharmaceutical primary standard
API family
disulfiram
manufacturer/tradename
EDQM
mp
69-71 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
CCN(CC)C(=S)SSC(=S)N(CC)CC
InChI
1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
InChI key
AUZONCFQVSMFAP-UHFFFAOYSA-N
Gene Information
human ... ALDH2(217)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Alcohol dehydrogenase inhibitor.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Boris Cvek et al.
Drug discovery today, 13(15-16), 716-722 (2008-06-27)
The major approach to the development of anticancer drugs involves searching for new compounds, efficient against malignancies, which are not, as yet, used clinically. This strategy is time-consuming and expensive. Recent studies have disclosed a surprising, but mechanistically consistent, anticancer
Colin Rae et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(6), 953-960 (2013-04-26)
Disulfiram has been used for several decades in the treatment of alcoholism. It now shows promise as an anticancer drug and radiosensitizer. Proposed mechanisms of action include the induction of oxidative stress and inhibition of proteasome activity. Our purpose was
Meriem Gaval-Cruz et al.
Molecular interventions, 9(4), 175-187 (2009-09-02)
The anti-alcoholism drug disulfiram (Antabuse), which is an inhibitor of aldehyde dehydrogenase, induces an aversive reaction to alcohol consumption and thereby helps patients reduce alcohol intake. Recent clinical trials, initiated to investigate whether disulfiram could be used to treat individuals
Parvinder Hothi et al.
Oncotarget, 3(10), 1124-1136 (2012-11-21)
Glioblastoma Multiforme (GBM) continues to have a poor patient prognosis despite optimal standard of care. Glioma stem cells (GSCs) have been implicated as the presumed cause of tumor recurrence and resistance to therapy. With this in mind, we screened a
Pier Paolo Pani et al.
The Cochrane database of systematic reviews, (1)(1), CD007024-CD007024 (2010-01-22)
Cocaine dependence is a disorder for which no pharmacological treatment of proven efficacy exists, advances in the neurobiology could guide future medication development. To evaluate the efficacy and the acceptability of disulfiram for cocaine dependence. We searched: PubMed, EMBASE, CINAHL
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