제품 이름
Bicinchoninic acid disodium salt hydrate, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
technique(s)
titration: suitable
color
white to light yellow
solubility
0.5% sodium bicarbonate: 50 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
SMILES string
O.[Na+].[Na+].[O-]C(=O)c1cc(nc2ccccc12)-c3cc(C([O-])=O)c4ccccc4n3
InChI
1S/C20H12N2O4.2Na.H2O/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;;/h1-10H,(H,23,24)(H,25,26);;;1H2/q;2*+1;/p-2
InChI key
FAFVGCAYKZKOPT-UHFFFAOYSA-L
Application
- Bicinchoninic acid disodium salt hydrate has been used to monitor the levels of reducing sugars, thereby helping in the detection of chitinases.
- It has also been used to determine the amount of cellulose reducing ends (micromoles/g cellulose).
- It has been used for determining protein concentration.
Biochem/physiol Actions
Bicinchoninic acid is used for the determination of protein concentration. It is responsible for the making of intense purple complex with cuprous ion (Cu+), in presence of alkaline conditions. The amount of Cu+ is in relation with the protein concentration.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Detection and characterization of chitinases and other chitin-modifying enzymes.
Howard MB, et al.
Journal of Industrial Microbiology & Biotechnology, 30, 627-635 (2003)
Prevention of rt-PA induced blood-brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice.
Teng F, et al.
Experimental Neurology, 248, 416-428 (2013)
Makon-Sébastien Njock et al.
Blood, 125(20), 3202-3212 (2015-04-04)
The blood contains high concentrations of circulating extracellular vesicles (EVs), and their levels and contents are altered in several disease states, including cardiovascular disease. However, the function of circulating EVs, especially the microRNAs (miRNAs) that they contain, are poorly understood.
