M2772
Menthol
99%
동의어(들):
2-Isopropyl-5-methylcyclohexanol, Hexahydrothymol
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C10H20O
CAS 번호:
Molecular Weight:
156.27
UNSPSC Code:
12352212
NACRES:
NA.25
PubChem Substance ID:
EC Number:
201-939-0
Beilstein/REAXYS Number:
3194263
MDL number:
vapor pressure
0.8 mmHg ( 20 °C)
Quality Level
assay
99%
bp
216 °C (lit.)
mp
34-36 °C (lit.)
density
0.89 g/mL at 25 °C (lit.)
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
CC(C)C1CCC(C)CC1O
InChI
1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3
InChI key
NOOLISFMXDJSKH-UHFFFAOYSA-N
Gene Information
human ... TRPA1(8989), TRPM8(79054)
General description
Menthol is a cyclic monoterpene alcohol, which is extracted from essential oils of Mentha canadensis and Mentha x piperita. It possesses antimicrobial, anticancer and anti-inflammatory properties. Menthol acts as a transient receptor potential cation channel (TRPM8) agonist. It also exhibits analgesic, antipruritic, anesthetic and cooling effects.
Menthol (C10H20O) is a terpenoid compound. It is extracted from the plants belonging to Mentha genus in the Lamiaceae family.
Application
Menthol has been used:
- to test its antifungal susceptibility
- to determine its efficacy as an anesthetic in fish
- to activate transient receptor potential cation channel (TRPM8)
- as an odorant for measuring sniffing dynamics
Biochem/physiol Actions
Menthol exhibits antifungal action on the membrane permeability and the cell wall consistency, this might leads to cell death or inhibition of the C. albicans filamentation. Therefore, it can be used as a potential therapeutic agent for candidiasis. In addition to antifungal activity, menthol also exhibits anesthetic, antispasmodic, anti-ulcer and antiviral properties. It is considered as a safe compound for animal life. Therefore, Menthol is widely used in pharmaceuticals, cosmetics and food industries.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
저장 등급
11 - Combustible Solids
flash_point_f
204.8 °F
flash_point_c
96 °C
ppe
dust mask type N95 (US), Eyeshields, Gloves
Efficacy of Benzocaine, Eugenol, and Menthol as Anesthetics for Freshwater Angelfish
Romaneli RD et al.
Journal of Aquatic Animal Health, 30(3), 210-216 (2018)
TRP channel mediated neuronal activation and ablation in freely behaving zebrafish
Chen S, et al.
Nature Methods, 13(2), 147-147 (2015)
Spontaneous rapid odor source localization behavior requires interhemispheric communication
Rabell JE, et al.
Current Biology, 27(10), 1542-1548 (2017)
Inhibitory effect of menthol on expression of aspartyl proteinase 1 in fluconazole-resistant Candida albicans
Shahrzad S and Alireza k
Journal of HerbMed Pharmacology, 8(1) (2019)
Inhibitory effect of menthol on expression of aspartyl proteinase 1 in fluconazole-resistant Candida albicans
Shahrzad S and Alireza K
Journal of HerbMed Pharmacology, 8(1) (2019)
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