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Merck

P1754

TWEEN® 80

viscous liquid

동의어(들):

TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
9005-65-6
UNSPSC Code:
12161900
NACRES:
NA.21
MDL number:
MFCD00082107

주요 문서

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기술 서비스
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도움 문의

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

biological source

Porcine (tallow), bovine (tallow)

description

non-ionic

form

viscous liquid

mol wt

micellar avg mol wt 79,000

Quality Level

200

composition

Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)

aggregation number

60

CMC

0.012 mM (20-25°C)

viscosity

400-620 mPa.s

transition temp

cloud point 65 °C

solubility

water: soluble, clear to slightly hazy, colorless to yellow

density

1.064 g/cm3

HLB

15

application(s)

cell analysis

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관련 카테고리

General description

Tween® 80 is a non-ionic detergent and surfactant, classified as an ester of sorbitan and oleic acid. It is a versatile compound commonly employed in various biological applications, including cell lysis, nuclei isolation, and cell fractionation. Additionally, Tween 80 finds use in stabilizing proteins and facilitating protein membrane studies. Its effectiveness stems from its membership in the polysorbate group, characterized by the combination of sorbitol and sorbitane oleic esters with polyethylene glycol chains. These structural features contribute to Tween 80′s emulsifying capabilities and a broad range of applications.

Application

Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines.
TWEEN® 80 has been used in drug vehicle solution for specific injections in mice and rats. It has been used for the determination of esterase activity in bacterial cells.

Biochem/physiol Actions

TWEEN® 80 is a polysorbate surfactant which helps in stabilizing proteins and in protein membrane studies. It is regularly used for the extraction of membrane proteins and isolation of nuclei from cells.

Features and Benefits

  • Excellent wetting and dispersing agent
  • Highly versatile surfactant for your Cell Biology and Biochemical research

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

TWEEN is a registered trademark of Croda International PLC

저장 등급

10 - Combustible liquids

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Eyeshields, Gloves

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시험 성적서(COA)

Lot/Batch Number
BCCH1857
BCCH1858
BCCG8649
WXBD6739V
WXBD2066V

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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문서 라이브러리 방문

Pathogenic factors of Pseudomonas cepacia isolates from patients with cystic fibrosis.
Gessner AR and Mortensen JE
Journal of Medical Microbiology, 33, 115-115 (1990)
Handbook of Biochemistry and Molecular Biology (2010)
Zandra Gerdes et al.
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The role of microplastic (MP) as a carrier of persistent organic pollutants (POPs) to aquatic organisms has been a topic of debate. However, the reverse POP transport can occur if relative contaminant concentrations are higher in the organism than in
Thibaut Frachon et al.
Langmuir : the ACS journal of surfaces and colloids, 32(49), 13009-13019 (2016-12-14)
Therapeutic proteins are privileged in drug development because of their exquisite specificity, which is due to their three-dimensional conformation in solution. During their manufacture, storage, and delivery, interactions with material surfaces and air interfaces are known to affect their stability.
Davidson JN
The Biochemistry of the Nucleic Acids (2012)
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