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PHR1005

Acetaminophen

Name: Acetaminophen
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

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크기 선택

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:

CH₃CONHC₆H₄OH

CAS 번호:

103-90-2

Molecular Weight:

151.16

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823036

EC Number:

203-157-5

Beilstein/REAXYS Number:

2208089

MDL number:

MFCD00002328

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도움 문의

속성

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. P030000, traceable to USP 1003009

API family

paracetamol, acetaminophen

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

168-172 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

Gene Information

human ... FAAH(2166), PTGS1(5742), PTGS2(5743), TRPV1(7442)

설명

General description

Acetaminophen is a drug, which possesses pharmacological properties like antipyretic and analgesic property.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Acetaminophen may be used as a standard in the determination of acetaminophen in human serum or plasma samples using spectrophotometric technique. It may also be used as a standard in the estimation of acetaminophen in pharmaceutical formulations using high performance liquid chromatography (HPLC).

Analgesic.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB7782 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

저장 등급

11 - Combustible Solids

flash_point_f

364.3 °F - Pensky-Martens closed cup

flash_point_c

184.6 °C - Pensky-Martens closed cup

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 분석 증명서(COA)를 검색하십시오. 로트 및 배치 번호는 제품 라벨의 ‘Lot’ 또는 ‘Batch’라는 단어 뒤에 기재되어 있습니다.

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문서 라이브러리 방문

Simultaneous high-performance liquid chromatographic stability-indicating analysis of acetaminophen and codeine phosphate in tablets and capsules

Sisco.RW, et al.

Journal of Chromatography A, 348, 253-263 (1985)

Spectrophotometric Screening Method for Acetaminophen in Serum and Plasma

Liu.ZT and Oka.HK

Clinical Chemistry, 26, 69-71 (1980)

Reversed-phase HPLC method for the estimation of acetaminophen, ibuprofen and chlorzoxazone in formulations

Ravisankar.S, et al.

Talanta, 46, 1577-1581 (1998)

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