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PHR1068

Ethylenediaminetetraacetic acid disodium salt dihydrate

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Edetate Disodium, Edetate disodium dihydrate, Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na2, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na2

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C10H14N2Na2O8 · 2H2O
CAS 번호:
6381-92-6
Molecular Weight:
372.24
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
205-358-3
Beilstein/REAXYS Number:
3900609
기술 서비스
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도움 문의

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. D2900000, traceable to USP 1233009

API family

edta

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

248 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Ethylenediaminetetraacetic acid disodium salt dehydrate may be used as a reference standard in validating the potential antioxidant activity and the total phenolic content of samples of seaweed extract via metal chelation technique using ferrous ion-chelating ability assay.
Ethylenediaminetetraacetic acid disodium salt dihydrate may be used as a pharmaceutical reference standard for the determination of ethylenediaminetetraacetic acid (EDTA) in pharmaceutical formulations using ion chromatography with suppressed conductimetric detection.
Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA5634 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H332,H373

Hazard Classifications

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

target_organs

Respiratory Tract

저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

EDTA determination in pharmaceutical formulations and canned foods based on ion chromatography with suppressed conductimetric detection
Krokidis AA, et al.
Analytica Chimica Acta, 535(1-2), 57-63 (2005)
Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds
Wang T, et al.
Food Chemistry, 116(1), 240-248 (2009)
Sabrina Lusvarghi et al.
Nucleic acids research, 41(13), 6637-6649 (2013-05-04)
Interaction between the viral protein Rev and the RNA motifs known as Rev response elements (RREs) is required for transport of unspliced and partially spliced human immunodeficiency virus (HIV)-1 and HIV-2 RNAs from the nucleus to the cytoplasm during the
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