PHR1107
L-Glutamic acid
Pharmaceutical Secondary Standard; Certified Reference Material
동의어(들):
(S)-2-Aminopentanedioic acid, Glu
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HO2CCH2CH2CH(NH2)CO2H
CAS 번호:
Molecular Weight:
147.13
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-293-7
Beilstein/REAXYS Number:
1723801
MDL number:
eCl@ss:
32160406
InChI key
WHUUTDBJXJRKMK-VKHMYHEASA-N
InChI
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
SMILES string
N[C@@H](CCC(O)=O)C(O)=O
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. G0355000, traceable to USP 1294976
API family
glutamic acid
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
205 °C (dec.) (lit.)
application(s)
cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
유사한 제품을 찾으십니까? 방문 제품 비교 안내
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
L-Glutamic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by ion chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7158 in the slot below. This is an example certificate only and may not be the lot that you receive.
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Ion-chromatographic determination of carbocisteine in pharmaceuticals based on non-suppressed conductimetric detection
Megoulas NC and Koupparis MA
Journal of Chromatography A, 1026(1-2), 167-174 (2004)
G Alfredsson et al.
Biological psychiatry, 23(7), 689-697 (1988-04-01)
The concentrations of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), 4-hydroxy-3-methoxyphenylglycol (HMPG), and glutamate were determined in cerebrospinal fluid (CSF) and serum in 10 healthy volunteers. The monoamine metabolites were measured by mass fragmentography and the glutamate by high-performance liquid chromatography.
Luigi F Agnati et al.
Pharmacological reviews, 55(3), 509-550 (2003-07-19)
The molecular basis for the known intramembrane receptor/receptor interactions among G protein-coupled receptors was postulated to be heteromerization based on receptor subtype-specific interactions between different types of receptor homomers. The discovery of GABAB heterodimers started this field rapidly followed by
Katarzyna Rogoz et al.
Molecular pharmacology, 85(2), 322-334 (2013-11-28)
The transient receptor potential cation channel subfamily V member 1 (TRPV1) is known as a thermosensor and integrator of inflammation-induced hyperalgesia. TRPV1 is expressed in a subpopulation of primary afferent neurons that express several different neurotransmitters. The role of the
Kimberly J Dougherty et al.
Neuron, 80(4), 920-933 (2013-11-26)
Locomotion is controlled by spinal networks that generate rhythm and coordinate left-right and flexor-extensor patterning. Defined populations of spinal interneurons have been linked to patterning circuits; however, neurons comprising the rhythm-generating kernel have remained elusive. Here, we identify an ipsilaterally
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