PHR1136
Guaiacol
Pharmaceutical Secondary Standard; Certified Reference Material
동의어(들):
2-Methoxyphenol, Catechol monomethyl ether, Pyrocatechol monomethyl ether
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(CH3O)C6H4OH
CAS 번호:
Molecular Weight:
124.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-964-7
Beilstein/REAXYS Number:
508112
MDL number:
InChI key
LHGVFZTZFXWLCP-UHFFFAOYSA-N
InChI
1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3
SMILES string
COc1ccccc1O
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0000619, traceable to USP 1300004
vapor density
4.27 (vs air)
vapor pressure
0.11 mmHg ( 25 °C)
API family
guaiacol
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
refractive index
n20/D 1.543 (lit.)
bp
205 °C (lit.)
Quality Level
density
1.129 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Guaiacol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC) and electroanalytical techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
Guaiacol, along with 2,4,6-trichloroanisole, is responsible for cork taint in wine. A method has been developed for extraction and quantitation of the two compounds.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB3328 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
저장 등급
11 - Combustible Solids
flash_point_f
194.0 °F - closed cup
flash_point_c
90 °C - closed cup
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup.
Grosa G, et al.
Journal of Pharmaceutical and Biomedical Analysis, 41(3), 798-803 (2006)
Electroanalytical determination of codeine in pharmaceutical preparations.
Garrido JMPJ, et al.
Analytical Letters, 35(15), 2487-2498 (2002)
K M Pruitt et al.
Analytical biochemistry, 191(2), 278-286 (1990-12-01)
Because of the important biological functions of peroxidases, there is growing interest in the measurement of their concentrations in various secretions. At present, there is no standard method which allows for comparisons in reported activities. This report describes procedures which
J C Tsibris et al.
Obstetrics and gynecology, 67(3), 316-320 (1986-03-01)
The specific activity of guaiacol peroxidase was measured daily in human cervical mucus, vaginal fluids, and saliva during 45 cycles in 31 women. Also determined were basal body temperatures and serum hormones (luteinizing hormone [LH], estradiol, progesterone). The guaiacol peroxidase
Joel D Mainland et al.
Nature neuroscience, 17(1), 114-120 (2013-12-10)
Humans have ~400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms in odorant receptors alter receptor function.
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