PHR1416
Sodium Citrate
Pharmaceutical Secondary Standard; Certified Reference Material
동의어(들):
Sodium citrate tribasic dihydrate, Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HOC(COONa)(CH2COONa)2 · 2H2O
CAS 번호:
Molecular Weight:
294.10
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-675-3
Beilstein/REAXYS Number:
6104939
MDL number:
InChI key
NLJMYIDDQXHKNR-UHFFFAOYSA-K
InChI
1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
SMILES string
O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to USP 1613859
API family
sodium citrate
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
>300 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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General description
Sodium citrate, also known as E331, is a tri-sodium salt of citric acid. In food products, it is commonly used as a flavor and preservative. In pharmaceutical formulations, it is used as a buffer, emulsifier and sequestering agent.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Sodium citrate may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, food and pharmaceutical formulations by titrimetry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3037 in the slot below. This is an example certificate only and may not be the lot that you receive.
저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Sodium citrate
Handbook of Pharmaceutical Excipients 6th edition Pharmaceutical Press, 640-642 (2009)
Sodium citrate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3574-3574 (2017)
Sodium citrate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 4069-4069 (2018)
Sara Svensson et al.
International journal of nanomedicine, 9, 775-794 (2014-02-20)
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