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Merck

PHR1557

Methylene Chloride

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Dichloromethane, Methylene chloride

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
CH2Cl2
CAS 번호:
75-09-2
Molecular Weight:
84.93
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823466
EC Number:
200-838-9
Beilstein/REAXYS Number:
1730800
MDL number:
MFCD00000881

주요 문서

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InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

InChI

1S/CH2Cl2/c2-1-3/h1H2

SMILES string

ClCCl

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1601441

vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

1223 °F

expl. lim.

22 %

packaging

ampule of 3x1.2 mL each

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

300

bp

39.8-40 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

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관련 카테고리

Application

Methylene Chloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas chromatography (GC) technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB7796 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

시험 성적서(COA)

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문서 라이브러리 방문

Methylene Chloride
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 5885-5885 (2018)
Accidental intoxication by dichloromethane at work place: Clinical case and literature review
Pacheco C, et al.
Journal of Acute Medicine, 6(2), 43-45 (2016)
Angharad M Roberts et al.
Science translational medicine, 7(270), 270ra6-270ra6 (2015-01-16)
The recent discovery of heterozygous human mutations that truncate full-length titin (TTN, an abundant structural, sensory, and signaling filament in muscle) as a common cause of end-stage dilated cardiomyopathy (DCM) promises new prospects for improving heart failure management. However, realization
K E Mauck et al.
Integrative and comparative biology, 54(2), 193-209 (2014-04-22)
Recent research suggests that plant viruses, and other pathogens, frequently alter host-plant phenotypes in ways that facilitate transmission by arthropod vectors. However, many viruses infect multiple hosts, raising questions about whether these pathogens are capable of inducing transmission-facilitating phenotypes in
Guilherme Asmar Alencar et al.
The Journal of clinical endocrinology and metabolism, 99(8), E1501-E1509 (2014-04-09)
Primary macronodular adrenal hyperplasia (PMAH) is a rare cause of Cushing's syndrome, usually characterized by functioning adrenal macronodules and increased cortisol production. Familial clustering of PMAH has been described, suggesting an inherited genetic cause for this condition. The aim of
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