SMB01383
PhIP
≥95% (HPLC)
동의어(들):
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C13H12N4
CAS 번호:
Molecular Weight:
224.26
UNSPSC Code:
12352100
NACRES:
NA.28
MDL number:
biological source
synthetic
Quality Level
assay
≥95% (HPLC)
form
solid
shipped in
2-8°C
storage temp.
2-8°C
SMILES string
NC1=NC2=NC=C(C3=CC=CC=C3)C=C2N1C
InChI
1S/C13H12N4/c1-17-11-7-10(9-5-3-2-4-6-9)8-15-12(11)16-13(17)14/h2-8H,1H3,(H2,14,15,16)
InChI key
UQVKZNNCIHJZLS-UHFFFAOYSA-N
General description
PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) is a dietary genotoxic carcinogen formed in heat processed meat and fish via the Maillard reaction. PhIP is a primary metabolite activated by CYP1A2 and N-acetyltransferase 1 or sulfotransferase to DNA reactive metabolite.
Biochem/physiol Actions
Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Yueliang Zhao et al.
Journal of agricultural and food chemistry, 69(46), 13933-13941 (2021-11-11)
The effects of the deacetylation degree (DD) of chitosan on heterocyclic aromatic amine formation were investigated in chemical models and beef patties. The results in model systems showed that at lower addition levels (10 mg), chitosan with 85% DD showed