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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C10H15N5O10P2
CAS 번호:
Molecular Weight:
427.20
PubChem Substance ID:
eCl@ss:
32160414
UNSPSC Code:
41106305
NACRES:
NA.55
EC Number:
200-392-5
MDL number:
Beilstein/REAXYS Number:
67722
Assay:
≥95% (HPLC)
Form:
powder
Storage temp.:
−20°C
InChI key
XTWYTFMLZFPYCI-KQYNXXCUSA-N
InChI
1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
assay
≥95% (HPLC)
form
powder
impurities
≤15.0% water (KFT)
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
human ... HSP90AA1(3320), P2RY1(5028)
SMILES string
Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
Application
Adenosine 5′-diphosphate (5′-ADP or ADP) was used as a test compound for studying the endothelium-dependent vascular response in salt sensitive (DS) and salt resistant Dahl rats (DR). The product was used to study the different P2-purinergic receptor subtypes on canine vascular smooth muscle and endothelium.
Biochem/physiol Actions
Adenosine 5′-diphosphate induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
N J Cusack et al.
British journal of pharmacology, 76(1), 221-227 (1982-05-01)
1 Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and noncompetitively inhibits stimulated human platelet adenylate cyclase; it has been suggested that these two effects are mediated by separate ADP receptors on the platelet surface. 2 Adenosine 5'-triphosphate and seven adenine
Yoshihiro Matsumura et al.
The Journal of biological chemistry, 288(43), 31069-31079 (2013-08-31)
The C terminus of Hsp70 interacting protein (CHIP) E3 ligase functions as a key regulator of protein quality control by binding the C-terminal (M/I)EEVD peptide motif of Hsp/c70(90) with its N-terminal tetratricopeptide repeat (TPR) domain and facilitating polyubiquitination of misfolded
W G Mayhan
Inflammation, 16(4), 295-305 (1992-08-01)
The goal of this study was to determine the role of the synthesis and release of nitric oxide in modulating alterations in microvascular permeability of the hamster cheek pouch in response to adenosine 5'-diphosphate and bradykinin. We used intra-vital fluorescent
R N Goldberg et al.
Biophysical chemistry, 40(3), 241-261 (1991-07-01)
The thermodynamic treatment of the disproportionation reaction of adenosine 5'-diphosphate to adenosine 5'-triphosphate and adenosine 5'-monophosphate is discussed in terms of an equilibrium model which includes the effects of the multiplicity of ionic and metal bound species and the presence
Thomas Cuisset et al.
Journal of the American College of Cardiology, 48(7), 1339-1345 (2006-10-03)
We analyzed the benefit of a 600-mg clopidogrel loading dose on platelet reactivity and clinical outcomes after stenting for non-ST-segment elevation acute coronary syndrome (NSTE ACS). High post-treatment platelet reactivity (HPPR = adenosine diphosphate 10 mumol x l(-1) [ADP]-induced platelet
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