17772
Retinol
≥95.0% (HPLC), ~2700 U/mg
동의어(들):
Axerophthol, Vitamin A, Vitamin A alcohol, Vitamin A1, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C20H30O
CAS 번호:
Molecular Weight:
286.45
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058018
UNSPSC Code:
12352205
EC Number:
200-683-7
MDL number:
Beilstein/REAXYS Number:
403040
biological source
synthetic
Quality Level
assay
≥95.0% (HPLC)
form
(Powder or Crystal with Lumps)
specific activity
~2700 U/mg
color
yellow to dark yellow
mp
61-63 °C (lit.)
shipped in
dry ice
storage temp.
−20°C
SMILES string
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1
InChI
1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChI key
FPIPGXGPPPQFEQ-OVSJKPMPSA-N
General description
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinol is biologically active in a wide range of processes.
Retinol or all-trans-retinol is a 20-carbon molecule with cyclohexenyl ring, a side chain with four double bonds (all in trans configuration) and an alcohol end group.
Application
Retinol has been used as a standard in ultra-performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS) for the vitamins detection and quantification.
Biochem/physiol Actions
Retinol and its derivatives exhibit anti-aging properties. Retinol is used for treating wrinkles and signs of aging. However, due to its photo instability and skin irritation potency, it is hardly used in cosmetic formulations. Retinol is also used as a therapeutic for dermatoses. Its deficiency leads to xerosis and follicular hyperkeratosis.
Other Notes
1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)
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signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Gloves