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Merck

31390

Dextran from Leuconostoc spp.

Mr ~70,000

동의어(들):

DEXTRAN 70

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(C6H10O5)n
CAS 번호:
9004-54-0
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
232-677-5
MDL number:
MFCD00130935

주요 문서

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SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

biological source

(Leuconostoc spp)

form

powder

mol wt

Mr ~70,000

loss

≤7% loss on drying

color

white

mp

483  °C ((901 °F ))

solubility

water: 0.75 g/5mL, clear

absorption

≤0.05 at 375 nm in H2O at 10%

storage temp.

room temp

Quality Level

200

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관련 카테고리

General description

Dextran is an extracellular bacterial polymer of D-glucopyranose. It primarily consists of α-(1→6) linkage in the main chain and a variable amount of α-(1→2), α-(1→3), α-(1→4) branched linkages.

Application

Dextran from Leuconostoc spp. has been used:
  • for the isolation of islets from pancreatic tissue by centrifugation
  • as a component of Earle′s bicarbonate buffer for placental perfusion
  • for the isolation of rat brain microvessels

Biochem/physiol Actions

Dextran is a, which is commercially used as a drug, particularly as a blood plasma volume expander. It is used as an adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Sephadex, a cross-linked dextran is broadly used for the separation and purification of protein. In the food industry, dextran found its use as a thickener for jam and ice cream. It inhibits the crystallization of sugar, thereby enhancing moisture retention. This helps in maintaining the flavor and appearance of various food items.

Other Notes

Enhances immunoprecipitation sensitivity
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

저장 등급

11 - Combustible Solids

ppe

Eyeshields, Gloves, type N95 (US)

flash_point_f

Not applicable

flash_point_c

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

M F Dumon et al.
Electrophoresis, 11(10), 846-851 (1990-10-01)
A modification of crossed immunoelectrophoresis for the analysis of plasma lipoproteins is described and is called polyacrylamide gel-crossed immunoelectrophoresis. The incorporation of albumin in the first-dimensional gel facilitates the transfer of the larger lipoproteins containing apolipoprotein B from the first-dimensional
Sin-Yu Yang et al.
Transplantation proceedings, 51(5), 1458-1462 (2019-06-04)
Subcutaneous pockets provide an extrahepatic transplant site for islet grafting to treat type 1 diabetes. However, a hypoxic environment may cause central necrosis to islets and lead to graft failure. Our previous studies focused on a pre-treated subcutaneous site with
Kai-Chiang Yang et al.
Biotechnology and bioengineering, 115(9), 2341-2355 (2018-05-20)
Transplantation of encapsulated porcine islets is proposed to treat type 1 diabetes. However, the envelopment of fibrous tissue and the infiltration of immune cells impair islet function and eventually cause implant failure. It is known that hemodialysis using an ethylene
W Michael Babinchak et al.
Nature communications, 11(1), 5574-5574 (2020-11-06)
Liquid-liquid phase separation (LLPS) of proteins that leads to formation of membrane-less organelles is critical to many biochemical processes in the cell. However, dysregulated LLPS can also facilitate aberrant phase transitions and lead to protein aggregation and disease. Accordingly, there
Diego Delgado et al.
Human gene therapy, 23(4), 345-355 (2012-02-03)
The goal of the present study was to analyze the potential application of nonviral vectors based on solid lipid nanoparticles (SLN) for the treatment of ocular diseases by gene therapy, specifically X-linked juvenile retinoschisis (XLRS). Vectors were prepared with SLN
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Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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