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Merck

61743

N-Lauroylsarcosine sodium salt

BioUltra, Molecular Biology, ≥99.0% (HPLC)

동의어(들):

N-lauroylsarcosine sodium salt, N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS 번호:
137-16-6
Molecular Weight:
293.38
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
57651862
EC Number:
205-281-5
Beilstein/REAXYS Number:
5322974
MDL number:
MFCD00042728

주요 문서

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InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

grade

Molecular Biology

description

anionic

product line

BioUltra

assay

≥99.0% (HPLC)

form

powder

mol wt

micellar avg mol wt 600, average mol wt 600

aggregation number

2

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

loss

≤1% loss on drying, 110 °C

pH

7.0-9.0 (25 °C, 1 M in H2O)

CMC

14.6 mM (20-25°C)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.2, λ: 280 nm Amax: 0.06

application(s)

sample preservation

Quality Level

200

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관련 카테고리

General description

The N-lauroylsarcosine sodium salt is applicable for processes that require tight control of elemental content. This product aids in the solubilization and separation of membrane proteins, glycoproteins, and the isolation of RNA and plasmids. N-lauroylsarcosine sodium salt serves as an antifoaming supplement or as a component of a lysing buffer of bacteria or other cells. It indicates the paramagnetic anisotropy sign change in the micelle mesophase. N-lauroylsarcosine sodium salt inhibits hexokinase and the bacterial flora of human saliva/gut at 0.25%. It also exhibits fungistatic activity in aqueous dispersion (1%). N-lauroylsarcosine (LS) is an anionic surfactant with protein denaturant potency that is structurally similar to sodium lauryl sulfate (SLS). It can inactivate herpes simplex virus (HSV) infectivity in vitro. It is used as a microbicide in topical vaginal formulations to block the transmission of HSV, human immunodeficiency virus type 1 (HIV-1), and possibly other pathogens causing sexually transmitted diseases (STDs).

Application

N-Lauroylsarcosine sodium salt has been used as a component:

  • of nuclease stop mix, embryo extract buffer to dissociate nonspecifically bound proteins from chromatin
  • of proteinase K solution for the heat denaturation of genomic DNA
  • of 10% (w/v) sarcosyl/0.5 M ethylenediaminetetraacetic acid (EDTA) solution to prepare EDTA-sarcosyl-proteinase (ESP) buffer
  • in the hybridization buffer for in situ hybridization histochemistry
  • in the embryo extract buffer to dissociate nonspecifically bound proteins from chromatin
  • in proteinase K solution to inactivate the enzymes

Other Notes

Anionic surfactant.

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

저장 등급

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

512.6 °F - closed cup

flash_point_c

267 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
BCCG4842
BCCF4825
BCCF0374
BCCC9502
BCCC0765

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