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Merck

61962

Betaine

BioUltra, ≥99.0% (NT)

동의어(들):

(Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(CH3)3N+CH2COO-
CAS 번호:
107-43-7
Molecular Weight:
117.15
UNSPSC Code:
41116107
NACRES:
NA.25
PubChem Substance ID:
57651874
EC Number:
203-490-6
Beilstein/REAXYS Number:
3537113
MDL number:
MFCD00012123

주요 문서

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InChI key

KWIUHFFTVRNATP-UHFFFAOYSA-N

InChI

1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3

SMILES string

C[N+](C)(C)CC([O-])=O

product line

BioUltra

assay

≥99.0% (NT)

impurities

insoluble matters, passes filter test

solubility

methanol: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤200 mg/kg, sulfate (SO42-): ≤200 mg/kg

cation traces

Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤100 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg, Ca: ≤20 mg/kg

absorption

≤0.05 at 280 nm in methanol at 1 M, ≤0.09 at 260 nm in methanol at 1 M

Quality Level

200

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관련 카테고리

Application

Betaine has been used in reverse transcription to increase the thermal stability of proteins and to destabilize the DNA helix.

Biochem/physiol Actions

Betaine has been shown to increase S-adenosylmethionine (SAM) levels and hence, may have a role in diminishing hepatic steatosis. It is an osmolyte which protects cells against environmental stress.
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

General description

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
BCCG8398
BCCF9050
BCCF4693
BCCF4079
BCCF2361

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Full-length RNA-seq from single cells using Smart-seq2.
Picelli S
Nature Protocols, 9(1), 171-181 (2014)
Varsha Mathur et al.
Current biology : CB, 29(17), 2936-2941 (2019-08-20)
The apicomplexans are a group of obligate animal pathogens that include Plasmodium (malaria), Toxoplasma (toxoplasmosis), and Cryptosporidium (cryptosporidiosis) [1]. They are an extremely diverse and specious group but are nevertheless united by a distinctive suite of cytoskeletal and secretory structures related to
Shangli Cheng et al.
Cell reports, 26(10), 2593-2607 (2019-03-07)
Following implantation, the epiblast (EPI) cells transit from the naive to primed pluripotency, accompanied by dynamic changes in X chromosome activity in females. To investigate the molecular attributes of this process, we performed single-cell RNA-seq analysis of 1,724 cells of
M R Olthof et al.
Current drug metabolism, 6(1), 15-22 (2005-02-22)
High plasma concentrations of homocysteine may increase risk of cardiovascular disease. Folic acid lowers plasma homocysteine by 25% maximally, because 5-methyltetrahydrofolate is a methyl donor in the remethylation of homocysteine to methionine. Betaine (trimethylglycine) is also a methyl donor in
W Abu Al-Soud et al.
Journal of clinical microbiology, 38(12), 4463-4470 (2000-12-02)
The full potential of diagnostic PCR is limited, in part, by the presence of inhibitors in complex biological samples that reduce the amplification efficiency. Therefore, different pre-PCR treatments are being used to reduce the effects of PCR inhibitors. The aim
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