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Merck

84797

Poly(ethylene glycol)

greener alternative

BioUltra, 2,000

동의어(들):

Polyethylene glycol, PEG

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
H(OCH2CH2)nOH
CAS 번호:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

product line

BioUltra

form

powder

mol wt

Mr 1900-2200

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

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impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

50-53 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: ≤0.1, λ: 280 nm Amax: ≤0.04

greener alternative category

Quality Level

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General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion. It exhibitsstealth effect, prolonged blood circulation and excellent biocompatibility. PEG has an ability to elicit hypersensitivity reactions via stimulating complement pathway.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly(ethylene glycol) has been used:
  • as a constituent in the preparation of liquid desiccant solutions
  • as a precipitating agent and additive in protein crystallization
  • as a representative biocompatible polymer to decipher its interactions with cellular system at molecular level

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target
Zhang B, et al.
Cell, 176(3), 636-648 (2019)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Exploring carbon nanomaterial diversity for nucleation of protein crystals
Govada L, et al.
Scientific Reports, 6(18), 20053-20053 (2016)
Influence of osmotic drying with an aqueous poly (ethylene glycol) liquid desiccant on alumina objects gelcast with gelatin
Hammel EC, et al.
Ceramics International, 43(18), 16443-16450 (2017)
Li Xu et al.
Biomaterials, 147, 1-13 (2017-09-20)
As the gold standard polymer for drug delivery system, polyethylene glycol (PEG) has excellent biocompatibility. It's reported that the low nonspecific interactions between PEG and body contribute to its biocompatibility. However, here we discover dynamic biological interactions exist between PEG

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