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Merck

89510

Poly(ethylene glycol)

greener alternative

BioUltra, 8,000

동의어(들):

Polyethylene glycol, PEG

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
H(OCH2CH2)nOH
CAS 번호:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

product line

BioUltra

form

solid

mol wt

Mr 7000-9000

Quality Level

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

61-64 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.09, λ: 280 nm Amax: 0.03

greener alternative category

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General description

Poly(ethylene glycol) (PEG) is a polymer of ethylene glycol units and is hydrophilic in nature. PEG has high hydration capacity and is structurally flexible. PEG has advantage as a drug conjugate due to biocompatibility and nonexistence of steric hindrances in its structure.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly(ethylene glycol) has been used:
  • in the transformation buffer in yeast
  • as a constituent of dengue virus isolation buffer
  • for concentration of lentivirus particles
  • in the crystallization of herpesvirus nuclear egress complex (NEC)

Biochem/physiol Actions

The Food and Drug Administration (FDA) approved PEG as drug conjugates, is nonimmunogenic and safe. PEG is widely used as a reagent in biochemistry and molecular biology experiments. PEG conjugation improves solubility and dissolution of diabetes drug, Gliclazide. It is used in carbon nanotube functionalization. The presence of PEG 8000 in the tannin tree foliage improves metabolisable energy (ME) content and gas production.

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 문서 section.

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Characterisation of gliclazide-PEG 8000 solid dispersions
Biswal S, et al.
Tropical Journal of Pharmaceutical Research, 8(5) (2009)
Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions
Zhang C, et al.
Scientific Reports, 7(1), 44708-44708 (2017)
A simple, inexpensive, robust and sensitive dot-blot assay for equal detection of the nonstructural-1 glycoprotein of all dengue virus serotypes
Falconar AK and Romero-Vivas CM
Virology Journal, 10(1), 126-126 (2013)
The effect of polyethylene glycol (PEG 8000) supplementation on in vitro gas production kinetics of leaves from tannin containing trees
Kamalak A, et al.
South African Journal of Animal Science, 35(4), 229-237 (2005)
Ananthakrishnan Soundaram Jeevarathinam et al.
Biosensors & bioelectronics, 126, 831-837 (2019-01-04)
Heparin is an indispensable drug in anticoagulation therapy but with a narrow therapeutic window, which dictates regular testing and dose adjustment. However, current monitoring tools have a long turnaround time or are operator intensive. In this work, we describe a

관련 콘텐츠

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

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