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Merck

93659

L-Tryptophan

≥99.5% (NT), BioUltra

동의어(들):

(S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C11H12N2O2
CAS 번호:
Molecular Weight:
204.23
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-795-6
MDL number:
Beilstein/REAXYS Number:
86197
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제품 이름

L-Tryptophan, BioUltra, ≥99.5% (NT)

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

InChI key

QIVBCDIJIAJPQS-VIFPVBQESA-N

SMILES string

N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

product line

BioUltra

assay

≥99.5% (NT)

form

powder or crystals

optical activity

[α]20/D −31.5±1°, c = 1% in H2O

impurities

insoluble matter, passes filter test

ign. residue

≤0.1%

loss

≤0.1% loss on drying, 20 °C (HV)

color

white

mp

280-285 °C (dec.) (lit.)

solubility

0.5 M HCl: 0.1 g/mL at 20 °C, clear, colorless to faintly yellow

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

absorption

cut-off at 326 nm in 0.5 M HCl at 0.5 M

application(s)

cell analysis

Quality Level

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Application

L-Tryptophan has been used as a nutritional supplement to study its effect on the circadian clock of primary cell lines. It has also been used as a test amino acid aerosol to study the variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols.

Biochem/physiol Actions

Tryptophan (Trp) is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.

Other Notes

Amino acid precursor of serotonin and melatonin
In tryptophan-substituted Sephadex® and Sepharose for the improved chromatographic separation of cellulases; As spacer in isotachophoresis of serum proteins; Growth requirement of various microorganisms.

Legal Information

Sephadex is a registered trademark of Cytiva
Sepharose is a trademark of Cytiva

저장 등급

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

T. Hine et al.
Electrophoresis ?83, 541-541 (1984)
M A Vijayalakshmi et al.
Journal of chromatography, 177(2), 201-208 (1979-09-21)
The adsorption of tyrosine, tryptophan and some related compounds on tryptophan and tryptophanyltryptophan gels is similar to but much stronger than that observed with the parent gel Sephadex G-25. The adsorption has been attributed mainly to charge transfer or redistribution
Long-lasting effect of perinatal exposure to L-tryptophan on circadian clock of primary cell lines established from male offspring born from mothers fed on dietary protein restriction.
Nascimento E
PLoS ONE, 8(2), 1-14 (2013)
CRC Handbook of Microbiology, 4, 1-1 (1974)
Variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols
Jae HeeJung and Jung EunLee
Journal of Aerosol Science, 65, 101-110 (2013)

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