A2093
Aspirin
meets USP testing specifications
동의어(들):
Acetylsalicylic acid, 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
2-(CH3CO2)C6H4CO2H
CAS 번호:
Molecular Weight:
180.16
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-064-1
Beilstein/REAXYS Number:
779271
MDL number:
InChI key
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
InChI
1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
SMILES string
CC(=O)Oc1ccccc1C(O)=O
agency
USP/NF, meets USP testing specifications
form
powder or crystals
mp
134-136 °C (lit.)
application(s)
pharmaceutical (small molecule)
Quality Level
Gene Information
human ... ITGA2B(3674), PTGS1(5742), PTGS2(5743)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
General description
Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug. It occurs as white crystalline powder and is derived from salicylic acid.
Application
Aspirin has been used:
- as a stabilizer for blood during 13,14-dihydro-15-keto-prostaglandin F2α (PGFM) measurement
- to evaluate cell viability of BV-2 microglial cell line
- in morphogenesis assay
Biochem/physiol Actions
Aspirin is an analgesic and antipyretic agent used in the treatment of fever and pain as in arthritis. It is also associated with cardiovascular diseases.
Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3
저장 등급
11 - Combustible Solids
flash_point_f
482.0 °F
flash_point_c
250 °C
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Concise Clinical Pharmacology (2007)
Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-kB, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells
Yang JM, et al.
Neuroscience, 275, 296-394 (2014)
The 100 Most Important Chemical Compounds: A Reference Guide (2011)
Relationship between endotoxin and prostaglandin (PGE2 and PGFM) concentrations and ovarian function in dairy cows with puerperal endometritis
Mateus L, et al.
Animal Reproduction Science (2003)
Henry's Clinical Diagnosis and Management by Laboratory Methods E-book (2011)
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