A5508
Adenosine 5′-phosphosulfate sodium salt
≥85%, synthetic (organic), powder
동의어(들):
APS
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C10H14N5O10PS
CAS 번호:
Molecular Weight:
427.28
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
Assay:
≥85%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear to hazy, colorless to light yellow
Storage temp.:
−20°C
제품 이름
Adenosine 5′-phosphosulfate sodium salt, ≥85%
Quality Level
SMILES string
[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OS(O)(=O)=O)C(O)C3O
InChI
1S/C10H14N5O10PS.Na.H/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-26(18,19)25-27(20,21)22;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H,20,21,22);;
InChI key
KLZADYTZAADWRW-UHFFFAOYSA-N
biological source
synthetic (organic)
assay
≥85%
form
powder
solubility
water: 50 mg/mL, clear to hazy, colorless to light yellow
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
shipped in
dry ice
storage temp.
−20°C
Application
Adenosine 5′-phosphosulfate sodium salt has been used in enzyme-linked bioluminescence assay for adenosine triphosphate (ATP) and pyrophosphate quantification.
Biochem/physiol Actions
Adenosine 5′ phosphosulfate (APS) is used as a substrate of adenosine triphosphate (ATP) sulfurylase to complete a PP(i)-recycling loop for exponential ATP amplification in firefly luciferase ATP luminescence assay and other pyrophosphate regeneration-dependent detection assays.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment
Villa BR, et al.
Circulation, 127(24), 2442-2451 (2013)
Novel bioluminescent assay of alkaline phosphatase using adenosine-3?-phosphate-5?-phosphosulfate as substrate and the luciferin-luciferase reaction and its application
Arakawa H, et al.
Analytical biochemistry, 314(2), 206-211 (2003)
Fumika Mi-Ichi et al.
PLoS neglected tropical diseases, 13(8), e0007633-e0007633 (2019-08-20)
Amoebiasis, caused by Entamoeba histolytica infection, is a global public health problem. However, available drugs to treat amoebiasis are currently limited, and no effective vaccine exists. Therefore, development of new preventive measures against amoebiasis is urgently needed. Here, to develop
Momoko Horikoshi et al.
PLoS genetics, 11(7), e1005230-e1005230 (2015-07-02)
Reference panels from the 1000 Genomes (1000G) Project Consortium provide near complete coverage of common and low-frequency genetic variation with minor allele frequency ≥0.5% across European ancestry populations. Within the European Network for Genetic and Genomic Epidemiology (ENGAGE) Consortium, we
Kenji Tanimura et al.
Blood, 125(18), 2835-2844 (2015-03-04)
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by thrombosis and/or pregnancy complications. β2-glycoprotein I (β2GPI) complexed with phospholipid is recognized as a major target for autoantibodies in APS; however, less than half the patients with clinical manifestations of APS
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