A9165

N-Acetyl-L-cysteine

Name: <I>N</I>-Acetyl-<SC>L</SC>-cysteine
Brand: SIGMA

≥99% (TLC), suitable for cell culture, BioReagent

동의어(들):

LNAC, NAC

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

Linear Formula:

HSCH₂CH(NHCOCH₃)CO₂H

CAS 번호:

616-91-1

Molecular Weight:

163.19

NACRES:

NA.26

PubChem Substance ID:

24891402

UNSPSC Code:

12352209

EC Number:

210-498-3

MDL number:

MFCD00004880

Beilstein/REAXYS Number:

1724426

주요 문서

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제품 이름

N-Acetyl-L-cysteine, suitable for cell culture, BioReagent

InChI key

PWKSKIMOESPYIA-BYPYZUCNSA-N

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

SMILES string

CC(=O)N[C@@H](CS)C(O)=O

product line

BioReagent

assay

≥99% (TLC)

form

powder

technique(s)

cell culture | mammalian: suitable

color

white to off-white

mp

106-108 °C (lit.)

solubility

H₂O: 100 mg/mL (with heating)

storage temp.

2-8°C

Quality Level

200

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Application

N-Acetyl-L-cysteine has been used as a component of intestinal basal medium for the culture of mouse intestinal stem cells and also as a component of expansion medium.

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

저장 등급

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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문서 라이브러리 방문

Derivation and long-term expansion of human endometrial and decidual organoids

Margherita Turco

Protocol Exchange, 2639-2644 (2017)

Isolation, Culture, and Maintenance of Mouse Intestinal Stem Cells

Kevin P. O?Rourke

Bio-protocol, 6(4), e1733-e1733 (2016)

Sustained Akt signaling in articular chondrocytes causes osteoarthritis via oxidative stress-induced senescence in mice.

Jing Xie et al.

Bone research, 7, 23-23 (2019-10-28)

Osteoarthritis (OA) is an age-related disorder that is strongly associated with chondrocyte senescence. The causal link between disruptive PTEN/Akt signaling and chondrocyte senescence and the underlying mechanism are unclear. In this study, we found activated Akt signaling in human OA

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

Meritxell Huch et al.

Nature, 494(7436), 247-250 (2013-01-29)

The Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon, stomach and hair follicles. A three-dimensional culture system allows long-term clonal expansion of single Lgr5(+) stem

Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells.

Suzanne M Cloonan et al.

Journal of medicinal chemistry, 58(11), 4494-4505 (2015-05-12)

Ruthenium polypyridyl complexes show great promise as new photodynamic therapy (PDT) agents. However, a lack of detailed understanding of their mode of action in cells poses a challenge to their development. We have designed a new Ru(II) PDT candidate that

모든 관련된 서류 보기

문서

3D Organoid Culture: New In Vitro Models of Development and Disease

Organoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.

Mitochondrial Stress and ROS

Cellular oxidative stress is countered by enzymatic scavengers and antioxidant modulators against reactive oxygen species damage.

L-Cysteine in Cell Culture

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Human Pancreatic Organoids for Cancer Research Applications

Human pancreatic cancer organoid biobank (PDAC organoids) with various KRAS mutations to aide in 3D cell culture and cancer research applications.

모두 보기

N-Acetyl-L-cysteine

≥99% (TLC), suitable for cell culture, BioReagent

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

제품 이름

InChI key

InChI

SMILES string

product line

assay

form

technique(s)

color

mp

solubility

storage temp.

Quality Level

관련 카테고리

설명

Application

Biochem/physiol Actions

Other Notes

안전성 정보

pictograms

signalword

hcodes

pcodes

Hazard Classifications

저장 등급

wgk

flash_point_f

flash_point_c

ppe

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