B2643

Biotinamidohexanoic acid N-hydroxysuccinimide ester

Name: Biotinamidohexanoic acid N-hydroxysuccinimide ester
Brand: SIGMA

≥98% (TLC), powder

동의어(들):

(+)-Biotinamidocaproate N-hydroxysuccinimidyl ester, N-(+)-Biotinyl-6-aminocaproic acid N-succinimidyl ester, N-(+)-Biotinyl-6-aminohexanoic acid NHS ester, N-Succinimidyl N-biotinyl-6-aminocaproate, Succinimidyl 6-(biotinamido)hexanoate

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₂₀H₃₀N₄O₆S

CAS 번호:

72040-63-2

Molecular Weight:

454.54

UNSPSC Code:

12352203

NACRES:

NA.46

PubChem Substance ID:

24891665

MDL number:

MFCD00065502

Beilstein/REAXYS Number:

3577403

주요 문서

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도움 문의

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도움 문의

InChI

1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)/t13-,14-,19-/m0/s1

SMILES string

[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2

InChI key

UVGHPGOONBRLCX-NJSLBKSFSA-N

assay

≥98% (TLC)

form

powder

solubility

H₂O: ≤2 mg/mL (with sonication), DMF: 50 mg/mL (Stable up to 2 months in dry DMF.)

storage temp.

−20°C

Quality Level

200

Application

Biotinamidohexanoic acid N-hydroxysuccinimide ester has been used in the biotinylation of antibodies.

Biochem/physiol Actions

Biotin is a label widely used in several biochemical applications and has a high affinity for avidin. A spacer chain is required to reduce steric hindrance while coupling biotin (a small molecule) to biopolymers (large molecules). Biotinamidohexanoic acid N-hydroxysuccinimide ester incorporates a 7-atom spacer with the N-succinimide leaving group. It can react with a primary amine in the pH range of 6.5-8.5. This biotinylation reagent incorporates an aminocaproyl spacer and thus can reduce the steric hindrance in binding avidin to some biotinylated compounds.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

wgk

WGK 3

저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay.

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The Biochemical journal, 401(2), 475-483 (2006-10-05)

PrPSc [abnormal disease-specific conformation of PrP (prion-related protein)] accumulates in prion-affected individuals in the form of amorphous aggregates. Limited proteolysis of PrPSc results in a protease-resistant core of PrPSc of molecular mass of 27-30 kDa (PrP27-30). Aggregated forms of PrP

Streptavidin paramagnetic particles provide a choice of three affinity-based capture and magnetic concentration strategies for retroviral vectors.

C Hughes et al.

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S M Costello et al.

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모든 관련된 서류 보기

Biotinamidohexanoic acid N-hydroxysuccinimide ester

≥98% (TLC), powder

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

InChI

SMILES string

InChI key

assay

form

solubility

storage temp.

Quality Level

관련 카테고리

설명

Application

Biochem/physiol Actions

Disclaimer

안전성 정보

wgk

저장 등급

flash_point_f

flash_point_c

ppe

문서

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