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Merck

B4429

BIS-TRIS

BioPerformance Certified, suitable for cell culture, suitable for insect cell culture, ≥98.0%

동의어(들):

2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol, 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol, Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C8H19NO5
CAS 번호:
Molecular Weight:
209.24
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
230-237-7
Beilstein/REAXYS Number:
2205275
MDL number:
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grade

BioPerformance Certified

assay

≥98.0%

form

crystalline powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

impurities

endotoxin and total aerobic microbial count, tested

useful pH range

5.8-7.2

pKa (25 °C)

6.5

mp

104 °C

solubility

H2O: 500 mg/mL, clear, colorless to very faintly yellow

anion traces

≤5 ppm

suitability

suitable for supravital staining of living blood cells

application(s)

diagnostic assay manufacturing

SMILES string

OCCN(CCO)C(CO)(CO)CO

InChI

1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2

InChI key

OWMVSZAMULFTJU-UHFFFAOYSA-N

General description

Bis-Tris is a zwitterionic buffer that is used in biochemistry and molecular biology research. It is structurally analogous to the the Good buffers that were developed to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The useful pH range of Bis-Tris is 5.8 - 7.2.

Application


  • A new test for the laboratory diagnosis of spherocytosis: This study introduces a novel diagnostic assay utilizing BIS-TRIS buffer, aimed at improving the detection and characterization of spherocytosis in clinical settings. The buffer′s stability and optimal pH make it suitable for routine use in clinical laboratories, contributing to accurate and reproducible diagnostic results (Vettore et al., 1984).

Features and Benefits

Features:
  1. Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
  2. Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
  3. M-Clarity Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity Program
  4. Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
  5. Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
  6. Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
    1. Site quality assessment
    2. ISO 9001 certificate
    3. Detailed product specifications
    4. Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)
Benefits:
  1. Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
  2. Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
  3. Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
  4. Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
  5. Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
  6. Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.

Other Notes

Easily compare specifications for BIS-TRIS products with the BIS-TRIS specification table.

Legal Information

M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

저장 등급

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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