C117
5-Carboxamidotryptamine maleate salt
powder, ≥98% (HPLC)
동의어(들):
5-CT, AH-21467
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C11H13N3O · C4H4O4
CAS 번호:
Molecular Weight:
319.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
H2O: 10 mg/mL
storage temp.
−20°C
SMILES string
OC(=O)\C=C/C(O)=O.NCCc1c[nH]c2ccc(cc12)C(N)=O
InChI
1S/C11H13N3O.C4H4O4/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10;5-3(6)1-2-4(7)8/h1-2,5-6,14H,3-4,12H2,(H2,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
PZQZSWAOVAMBQM-BTJKTKAUSA-N
Gene Information
human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR2A(3356), HTR2C(3358), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)
rat ... Htr7(65032)
Biochem/physiol Actions
Agonist at 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5 and 5-HT7 serotonin receptors.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Andrea Hembre Ulsund et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 3870-3886 (2018-12-07)
According to early models of GPCR signaling, G proteins only interact with activated receptors. However, some GPCRs were shown to assemble with G proteins before receptor activation, in accordance with more recent models. Previously, we found that the 5-HT7 receptor
Omkar L Patkar et al.
Addiction biology, 24(4), 652-663 (2018-07-20)
Repeated cycles of binge-like alcohol consumption and abstinence change the activity of several neurotransmitter systems. Some of these changes are consolidated following prolonged alcohol use and are thought to play an important role in the development of dependence. We have
Kirsten E Hoff et al.
PloS one, 13(8), e0203198-e0203198 (2018-08-30)
Mutations in mitochondrial DNA (mtDNA) have been linked to a variety of metabolic, neurological and muscular diseases which can present at any time throughout life. MtDNA is replicated by DNA polymerase gamma (Pol γ), twinkle helicase and mitochondrial single-stranded binding
Ayako Moritomo et al.
Bioorganic & medicinal chemistry, 22(15), 4323-4337 (2014-06-12)
We previously reported that the novel dual 5-HT₂B and 5-HT7 receptor antagonist N-(9-hydroxy-9H-fluorene-2-carbonyl)guanidine (4) exerted a suppressing effect on 5-HT-induced dural protein extravasation in guinea pigs. To develop a synthetic strategy, we performed docking studies of lead compound 4 bound
W L Bacon et al.
The Journal of pharmacology and experimental therapeutics, 294(2), 672-679 (2000-07-20)
The 5-hydroxytryptamine(7) (5-HT(7)) receptor was originally defined by molecular biology techniques. The 5-HT(7) receptor protein and mRNA are found in brain areas, such as the CA3 subfield of the hippocampus, that are involved in various neuropsychiatric disease states. No functional
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.