D4641
n-Dodecyl β-D-maltoside
≥98% (GC)
동의어(들):
DDM, Lauryl-β-D-maltoside
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C24H46O11
CAS 번호:
Molecular Weight:
510.62
NACRES:
NA.25
PubChem Substance ID:
eCl@ss:
32190102
UNSPSC Code:
12161900
MDL number:
Beilstein/REAXYS Number:
55318
InChI key
NLEBIOOXCVAHBD-QKMCSOCLSA-N
SMILES string
CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O
InChI
1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1
biological source
corn
description
non-ionic
assay
≥98% (GC)
form
powder
mol wt
micellar avg mol wt 50,000
aggregation number
98
technique(s)
protein quantification: suitable
impurities
<1.5% water (Karl Fischer)
CMC
0.15 mM (20-25°C)
mp
224-226 °C (lit.)
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless
storage temp.
−20°C
Quality Level
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General description
N-dodecyl-β-D-maltoside, also known as Lauryl Maltoside, stands as a non-ionic surfactant and derivative of pyrene (Py). Functioning as an alkyl maltopyranoside detergent, it excels particularly in the solubilization and crystallization of membrane proteins, making it a crucial tool in cell biology and biochemical research. Its unique capability arises from its adeptness at forming micelles that mimic the membrane environment, thereby preserving the α-helical structures and native conformations of membrane-associated proteins.
In addition to its primary function, N-dodecyl-β-D-maltoside has diverse applications, including the purification and stabilization of RNA polymerase, the detection of protein-lipid interactions, and serving as a substrate for glucosyl and xylosyl transfer by glycogenin. Its mild and non-denaturing properties have further led to its utilization in protein-anesthetic studies. Overall, N-dodecyl-β-D-maltoside emerges as a versatile detergent with a broad range of applications in membrane protein research and beyond. Its pivotal role in preserving protein structure and function establishes it as an indispensable tool for exploring the intricacies of membrane biology.
In addition to its primary function, N-dodecyl-β-D-maltoside has diverse applications, including the purification and stabilization of RNA polymerase, the detection of protein-lipid interactions, and serving as a substrate for glucosyl and xylosyl transfer by glycogenin. Its mild and non-denaturing properties have further led to its utilization in protein-anesthetic studies. Overall, N-dodecyl-β-D-maltoside emerges as a versatile detergent with a broad range of applications in membrane protein research and beyond. Its pivotal role in preserving protein structure and function establishes it as an indispensable tool for exploring the intricacies of membrane biology.
Application
n-Dodecyl β-D-maltoside has been used in a study to assess the mapping of unfolding states of integral helical membrane proteins by GPS-NMR and scattering techniques.
Non-ionic detergent for the stabilization and activation of enzymes and for membrane research.
Non-ionic detergent used to extract and solubilize proteins.
Features and Benefits
- Highly versatile surfactant for your cell biology and biochemical research
- Suitable for protein quantification
Other Notes
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저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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