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E1253

Estriol

Name: Estriol
Brand: SIGMA

synthetic (organic), ≥97%, immunomodulatory , powder

동의어(들):

1,3,5(10)-Estratriene-3,16α,17β-triol, 16α-Hydroxyestradiol, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₈H₂₄O₃

CAS 번호:

50-27-1

Molecular Weight:

288.38

NACRES:

NA.77

PubChem Substance ID:

24894396

UNSPSC Code:

51111800

EC Number:

200-022-2

MDL number:

MFCD00003691

Beilstein/REAXYS Number:

2508172

Assay:

≥97%

Form:

powder

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속성

제품 이름

Estriol, ≥97%

biological source

synthetic (organic)

Quality Segment

200

sterility

non-sterile

assay

≥97%

form

powder

mp

280-282 °C (lit.)

solubility

pyridine: 50 mg/mL, clear, colorless to faintly brownish-yellow

shipped in

ambient

storage temp.

room temp

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

InChI key

PROQIPRRNZUXQM-ZXXIGWHRSA-N

Gene Information

human ... SERPINA6(866)
mouse ... Esr1(13982)
rat ... Ar(24208)

설명

Application

Estriol has been used as a sex hormone to determine its binding constants to insulin (INS), the insulin receptor (IR), and INS-like peptides derived from the IR.

Biochem/physiol Actions

Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and estrone are produced by the placenta during pregnancy. These are also the primary estrogens produced by adipose tissue in men and post-menopausal women. Estriol may exhibit immunomodulatory benefits against various diseases such as autoimmune, inflammatory, and neurodegenerative conditions.