E1260
L-Ethionine
≥99% (TLC)
동의어(들):
L-2-Amino-4-(ethylthio)butyric acid
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
C2H5SCH2CH2CH(NH2)CO2H
CAS 번호:
Molecular Weight:
163.24
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
235-966-4
MDL number:
제품 이름
L-Ethionine, ≥99% (TLC)
assay
≥99% (TLC)
form
powder
color
white
mp
280 °C (dec.) (lit.)
storage temp.
−20°C
SMILES string
CCSCC[C@H](N)C(O)=O
InChI
1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChI key
GGLZPLKKBSSKCX-YFKPBYRVSA-N
Biochem/physiol Actions
An analog of methionine that interferes with the normal methylation of DNA and other methylation pathways, and induces pancreatic toxicity and liver cancer. However, in animal studies, it has also been shown to act synergistically with methionine-depletion to block the growth and metastasis of methionine-dependent tumors.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
문서
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.