E6511
Ethylenediaminetetraacetic acid tetrasodium salt dihydrate
BioReagent, suitable for cell culture, 98.5-102.0%
동의어(들):
EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate dihydrate
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · 2H2O
CAS 번호:
Molecular Weight:
416.20
UNSPSC Code:
12352204
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-573-9
Beilstein/REAXYS Number:
3861753
MDL number:
InChI
1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4
InChI key
KSYNLCYTMRMCGG-UHFFFAOYSA-J
SMILES string
O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
product line
BioReagent
assay
98.5-102.0%
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 160 mg/mL
shipped in
ambient
storage temp.
room temp
Quality Level
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General description
Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions. It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production. EDTA is an inhibitor of metalloprotease. It has anticoagulant property.
Application
Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:
- as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood
- as a chelator in animal and testicular cell isolation
- as a chelator for the culture of neural stem cells
Biochem/physiol Actions
Ethylenediaminetetraacetic acid (EDTA) is used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2
target_organs
Respiratory Tract
저장 등급
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction (2013)
Human Endometrial Stem Cell Isolation from Endometrium and Menstrual Blood
Tavakol S, et al.
Bio-protocol, 8(2) (2018)
What is the best protocol to cryopreserve immature mouse testicular cell suspensions?
Onofre J, et al.
Reproductive Biomedicine Online, 37(1), 6-17 (2018)
Modulation of matrix metalloproteinase activity by EDTA prevents posterior capsular opacification
Hazra S, et al.
Molecular Vision, 18(6), 1701-1701 (2012)
EDTA: the chelating agent under environmental scrutiny
Oviedo C and Rodriguez J
Quimica nova, 26(6), 901-905 (2003)
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