E9004
α-Ecdysone
≥90%, Insect molting hormone, powder
동의어(들):
2β,3β,14α,22(R),25-Pentahydroxy-7-cholesten-6-one
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C27H44O6
CAS 번호:
Molecular Weight:
464.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
222-760-4
MDL number:
Beilstein/REAXYS Number:
2422986
제품 이름
α-Ecdysone, ≥90%
InChI key
UPEZCKBFRMILAV-JMZLNJERSA-N
InChI
1S/C27H44O6/c1-15(20(28)8-9-24(2,3)32)16-7-11-27(33)18-12-21(29)19-13-22(30)23(31)14-25(19,4)17(18)6-10-26(16,27)5/h12,15-17,19-20,22-23,28,30-33H,6-11,13-14H2,1-5H3/t15-,16+,17-,19-,20+,22+,23-,25+,26+,27+/m0/s1
SMILES string
[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3(O)C1=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]24C)[C@H](C)[C@H](O)CCC(C)(C)O
sterility
non-sterile
assay
≥90%
form
powder
solubility
methanol: 20 mg/mL, clear, colorless to faintly yellow
application(s)
agriculture
environmental
shipped in
ambient
storage temp.
−20°C
Quality Level
관련 카테고리
General description
α-Ecdysone is a phytoecdysteroid, synthesized from cholesterol, and one of the major insect molting hormones. Ecdysone is secreted by the ecdysial glands present in insects.
Application
α-Ecdysone has been used:
- to study its effects on Drosophila melanogaster′s sexual maturation
- to study its effects on specification of neurons in Drosphila male-specific neurite
- as a standard to evaluate the ecdysteroid levels by liquid chromatography-mass spectrometry (LC-MS/MS)
Biochem/physiol Actions
Ecdysone exerts its effects via the ecdysone receptor and regulates larval molting, reproduction, and metamorphosis in insects.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Florentina Rus et al.
The EMBO journal, 32(11), 1626-1638 (2013-05-09)
Throughout the animal kingdom, steroid hormones have been implicated in the defense against microbial infection, but how these systemic signals control immunity is unclear. Here, we show that the steroid hormone ecdysone controls the expression of the pattern recognition receptor
Laura Boulan et al.
Current biology : CB, 23(6), 473-478 (2013-03-13)
During the development of multicellular organisms, body growth is controlled at the scale of the organism by the activity of long-range signaling molecules, mostly hormones. These systemic factors coordinate growth between developing tissues and act as relays to adjust body
Naoki Yamanaka et al.
Annual review of entomology, 58, 497-516 (2012-10-18)
The steroid hormone ecdysone is the central regulator of insect developmental transitions. Recent new advances in our understanding of ecdysone action have relied heavily on the application of Drosophila melanogaster molecular genetic tools to study insect metamorphosis. In this review
Jean-Philippe Parvy et al.
Development (Cambridge, England), 141(20), 3955-3965 (2014-09-26)
In most animals, steroid hormones are crucial regulators of physiology and developmental life transitions. Steroid synthesis depends on extrinsic parameters and autoregulatory processes to fine-tune the dynamics of hormone production. In Drosophila, transient increases of the steroid prohormone ecdysone, produced
Takumi Kayukawa et al.
Developmental biology, 388(1), 48-56 (2014-02-11)
Juvenile hormone (JH) has an ability to repress the precocious metamorphosis of insects during their larval development. Krüppel homolog 1 (Kr-h1) is an early JH-inducible gene that mediates this action of JH; however, the fine hormonal regulation of Kr-h1 and
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.